PMID: 11918468Mar 29, 2002Paper

West's syndrome

Journal of Child Neurology
W Donald Shields

Abstract

West's syndrome (infantile spasms) can be considered the classic disorder of the catastrophic childhood epilepsies. Although West's syndrome was identified 160 years ago, it is still not fully understood today. Because of the multiple etiologies associated with West's syndrome, the evaluation and treatment of the disease are complex, and, to date, there are no drugs approved by the US Food and Drug Administration specifically for the treatment of infantile spasms. The multiple etiologies associated with infantile spasms require that physicians take a broad look at all therapeutic options. There are, however, logical sequences that physicians should pursue when trying to treat this disorder. This article reviews the etiologies associated with West's syndrome, antiepilepsy drug therapies currently being used to treat the syndrome, and other treatment options available to clinicians.

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Citations

Jun 11, 2008·Head & Face Medicine·Tareq Abu Saleh, Lawrence Stephen
Jul 31, 2003·Epilepsia·Giuseppe CapovillaGiangennero Coppola
Jan 26, 2005·Brain & Development·Pratibha Singhi, Munni Ray
Aug 31, 2006·Yonsei Medical Journal·Young-Se KwonByong-Kwan Son
Oct 19, 2004·Lancet Neurology·Christian E ElgerMartin Kurthen
Mar 23, 2004·Journal of Child Neurology·Konstantinos VoudrisAngeliki Skardoutsou
Jul 1, 2004·Journal of Child Neurology·Sabrina BuoniAlberto Fois
Jul 9, 2010·Epilepsia·John M PellockJames W Wheless

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