"Wet suction technique (WEST)": a novel way to enhance the quality of EUS-FNA aspirate. Results of a prospective, single-blind, randomized, controlled trial using a 22-gauge needle for EUS-FNA of solid lesions

Gastrointestinal Endoscopy
Rajeev AttamNalini M Guda

Abstract

Contemporary EUS-guided FNA techniques involve the use of a needle, with an air column within the lumen, with or without suction. We describe a novel technique with an aim to improve the quality of the aspirate. To compare a novel "wet suction" technique (WEST) with the conventional FNA technique (CFNAT) of EUS-guided FNA using a 22-gauge FNA needle. Prospective, single-blind, and randomized trial. Two large tertiary-care hospitals. All consecutive adult patients presenting for EUS with possible FNA of solid lesions were offered the chance to participate in the study. All lesions were sampled with the same needle by using alternating techniques. Patients were randomized to the WEST versus the CFNAT for the first pass. If the first pass was made with the WEST, the second pass was made with the CFNAT, and subsequent passes were made in an alternating manner by using the same sequence. All FNAs were performed using 22-gauge needles. Specimen adequacy, cellularity, and blood contamination of EUS-guided FNA aspirates graded on a predefined scale. The WEST yielded significantly higher cellularity in a cell block compared with the CFNAT, with a mean cellularity score of 1.82±0.76 versus 1.45±0.768 (P<.0003). The WEST cell block result...Continue Reading

References

Dec 31, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Janak N ShahMichael L Kochman
Aug 1, 1930·Annals of Surgery·H E Martin, E B Ellis
Jun 2, 2012·World Journal of Gastroenterology : WJG·Jean-Marc DumonceauPaul Fockens
Jan 17, 2014·Digestive Diseases and Sciences·Yousuke NakaiKazuhiko Koike

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Citations

Feb 18, 2016·Endoscopic Ultrasound·Nicolas A VillaIsaac Raijman
Feb 3, 2016·Lancet·Terumi KamisawaKyoichi Takaori
Jan 6, 2017·Archives of Pathology & Laboratory Medicine·Michelle D ReidN Volkan Adsay
Feb 22, 2018·Cancers·Pujan Kandel, Michael B Wallace
Aug 29, 2018·Cytopathology : Official Journal of the British Society for Clinical Cytology·Aruna Nambirajan, Deepali Jain
Feb 28, 2019·Journal of Gastroenterology·Pujan Kandel, Michael B Wallace
Jun 14, 2019·Gastroenterology Research and Practice·Kazuhiro MizukamiKazunari Murakami
May 18, 2019·Archives of Pathology & Laboratory Medicine·Kenneth P H Pritzker, Heikki J Nieminen
Feb 9, 2016·World Journal of Gastroenterology : WJG·Stefania De Lisi, Marc Giovannini
Jan 3, 2018·Gut and Liver·Tiing Leong AngLai Mun Wang
Nov 8, 2016·World Journal of Gastroenterology : WJG·Andrew C Storm, Linda S Lee
Mar 29, 2020·World Journal of Gastrointestinal Endoscopy·Kemmian D JohnsonBenjamin Tharian
Dec 10, 2019·Clinical Endoscopy·Jae Keun Park, Kwang Hyuck Lee
Oct 6, 2020·Endoscopy International Open·Benedetto MangiavillanoAlessandro Repici
May 23, 2018·World Journal of Gastroenterology : WJG·Lulu ZhangAlina Stoita
Feb 2, 2019·Current Gastroenterology Reports·Shaffer R S Mok, David L Diehl
Jul 14, 2020·Endoscopic Ultrasound·Bojan Kovacevic, Peter Vilmann
Dec 2, 2020·Diagnostics·Atsushi KannoHironori Yamamoto
Nov 5, 2020·Diagnostics·Masahiro ItonagaMasayuki Kitano
Oct 13, 2020·Gastrointestinal Endoscopy·Soorya N AggarwalHiral N Shah
May 6, 2021·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Raquel Herranz PérezCecilio Santander
Jul 8, 2021·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Atsushi KannoHironori Yamamoto
Mar 19, 2021·European Journal of Gastroenterology & Hepatology·Inês PitaPedro Bastos
Jun 1, 2021·GE Portuguese Journal of Gastroenterology·Susana MarquesJacques Devière

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