Abstract
The physiological background of exercise-induced muscle fatigue(EIMUF) is only poorly understood. Thus, monitoring of EIMUF by a single or multiple biomarkers(BMs) is under debate. After a systematic literature review 91 papers were included. EIMUF is mainly due to depletion of substrates, increased oxidative stress, muscle membrane depolarisation following potassium depletion, muscle hyperthermia, muscle damage, impaired oxygen supply to the muscle, activation of an inflammatory response, or impaired calcium-handling. Dehydration, hyperammonemia, mitochondrial biogenesis, and genetic responses are also discussed. Since EIMUF is dependent on age, sex, degree of fatigue, type, intensity, and duration of exercise, energy supply during exercise, climate, training status (physical fitness), and health status, BMs currently available for monitoring EIMUF have limited reliability. Generally, wet, volatile, and dry BMs are differentiated. Among dry BMs of EIMUF the most promising include power output measures, electrophysiological measures, cardiologic measures, and questionnaires. Among wet BMs of EIMUF those most applicable include markers of ATP-metabolism, of oxidative stress, muscle damage, and inflammation. VO2-kinetics are used...Continue Reading
References
Aug 1, 1989·Ergonomics·H A deVriesM W Tichy
Jan 1, 1986·European Journal of Applied Physiology and Occupational Physiology·M CallowM Guppy
Aug 1, 1985·Clinical Science·L MakridesN L Jones
May 1, 1983·Journal of the Neurological Sciences·R S HikidaD L Costill
Aug 1, 1997·Journal of Applied Physiology·K WassermanY Y Zhang
Mar 19, 2002·The Journal of Physiology·Richard G CarsonNosratollah Shahbazpour
Jan 23, 2004·Cardiovascular Research·B J BehnkeT I Musch
Jul 7, 2005·Physiological Genomics·Xiaoli ZhaoMarco Brotto
Jul 12, 2005·Exercise and Sport Sciences Reviews·Mark A Febbraio, Bente K Pedersen
Feb 24, 2006·Clinical Physiology and Functional Imaging·Jean Guillaume SteinbergYves Jammes
Jul 19, 2006·Pediatrics·Michelle P HudspethThomas O Crawford
Dec 13, 2006·Biomedizinische Technik. Biomedical Engineering·Reinhard RzannyWerner A Kaiser
Dec 13, 2006·The Journal of Nutritional Biochemistry·Jonathan M PeakeJeff S Coombes
Aug 19, 2007·The Journal of Biological Chemistry·Christoph HandschinBruce M Spiegelman
Oct 25, 2007·Biochemical Society Transactions·B K Pedersen
Nov 28, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M J ZwartsB G M van Engelen
Dec 13, 2007·Journal of Sports Sciences·Alberto RainoldiMarco Alessandro Minetto
Apr 2, 2008·The European Respiratory Journal·H R Gosker, A M W J Schols
Sep 18, 2008·Journal of the American Geriatrics Society·Thomas W StorerShalender Bhasin
Nov 8, 2008·IEEE Transactions on Bio-medical Engineering·Jonathan B DingwellJoel D Trinity
Dec 24, 2008·Journal of Biomechanical Engineering·Miao SongDavid Chelidze
Dec 25, 2008·Physiological Genomics·Ayesha SaleemDavid A Hood
Mar 17, 2009·Clinical Biomechanics·Mario CifrekSasa Ostojić
May 22, 2009·Journal of Internal Medicine·Y JammesF Brégeon
Jul 10, 2009·Annals of Biomedical Engineering·Emma Fortune, Madeleine M Lowery
Dec 17, 2009·Respiratory Medicine·L D CalvertS J Singh
Mar 13, 2010·Journal of Biomedicine & Biotechnology·Claus Brandt, Bente K Pedersen
Apr 14, 2010·Journal of Strength and Conditioning Research·Athanasios ChatzinikolaouKyriakos Taxildaris
Jul 1, 2010·International Journal of Sports Medicine·J M ZunigaG O Johnson
Aug 13, 2010·Journal of Strength and Conditioning Research·Christopher P McLellanGregory C Gass
Sep 8, 2010·European Journal of Applied Physiology·Bruno GrassiJerzy A Zoladz
Oct 12, 2010·Journal of Strength and Conditioning Research·Marco MachadoAndré N Monteiro
Mar 23, 2011·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·David StewartAndrea Macaluso
Mar 23, 2011·Free Radical Biology & Medicine·Zhihui FengJiankang Liu
Mar 24, 2011·Sports Medicine·Axel J KnickerSimeon P Cairns
Apr 14, 2011·International Journal of Sports Physiology and Performance·Daniel A BoullosaFernando Lusquiños
May 14, 2011·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Glauber Ribeiro PereiraJurandir Nadal
May 17, 2011·Gait & Posture·Jeff A NesslerMary McDougal
Jul 30, 2011·European Journal of Applied Physiology·Esteban M GorostiagaMikel Izquierdo
Aug 24, 2011·European Journal of Applied Physiology·J P J SchmitzD F Stegeman
Sep 23, 2011·Sports Biomechanics·Andrew J Harrison
Nov 15, 2011·Chronobiology International·Omar HammoudaNizar Souissi
Apr 11, 2012·Clinical Physiology and Functional Imaging·Renato Molina, Benedito S Denadai
Apr 28, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Efthalia KerasiotiVaios Karathanos
Jul 14, 2012·International Journal of Sports Medicine·O HammoudaN Souissi
Aug 18, 2012·PloS One·Juan Del CosoBenito Pérez-González
Oct 20, 2012·European Journal of Applied Physiology·Simon WalkerKeijo Häkkinen
Nov 10, 2012·BMC Musculoskeletal Disorders·Josef Finsterer
Dec 5, 2012·Neuromuscular Disorders : NMD·John Vissing, Ronald G Haller
Mar 6, 2013·PloS One·Juan Del CosoBenito Pérez-González
Citations
Dec 20, 2016·Scientific Reports·Nobuhiro MaruyamaYo-Ichi Nabeshima
Feb 2, 2018·Journal of Clinical Medicine·Josef Finsterer, Sinda Zarrouk-Mahjoub
Oct 31, 2017·Research in Sports Medicine·Diego Marqués-JiménezNicolás Terrados
Feb 8, 2019·Journal of Applied Physiology·Karsten KrügerCarsten Zeilinger
Jan 7, 2020·Journal of Back and Musculoskeletal Rehabilitation·Houyong ZhongCuimei Wang
Apr 12, 2020·Molecular Nutrition & Food Research·Yang LiuMantian Mi
Nov 12, 2019·Frontiers in Genetics·Ana Paula Rennó SierraMaria Fernanda Cury-Boaventura
Jul 17, 2020·Physiological Research·A StožerL Križančić Bombek
Sep 25, 2019·Research : a Science Partner Journal·Fidias E Leon-SarmientoZeng Y Wang
Nov 30, 2018·Sports·George TheofilidisChristina Karatzaferi
Jul 5, 2018·Nutrients·Xi XuJianfa Zhang
Jul 19, 2020·Scientific Reports·Thomas ReichelKarsten Krüger
Jun 3, 2021·International Journal of Environmental Research and Public Health·Sebastian HackerKarsten Krüger