What accounts for ethnic differences in newborn skinfold thickness comparing South Asians and White Caucasians? Findings from the START and FAMILY Birth Cohorts

International Journal of Obesity : Journal of the International Association for the Study of Obesity
S S AnandK K Teo

Abstract

South Asians are a high-risk group for type 2 diabetes and coronary heart disease. We sought to determine ethnic differences in newborn adiposity comparing South Asians (SA) to White Caucasians (Whites). Seven hundred ninety pregnant women (401 SA, 389 Whites) and their full-term offspring from two birth cohorts in Canada were analyzed. Pregnant women completed a health assessment including a 75-g oral glucose tolerance test to assess for dysglycemia. Birthweight, length, waist and hip circumference, and triceps and subscapular skinfold thickness (a surrogate measure of body adiposity) were measured in all newborns. Multivariate regression was used to identify maternal factors associated with newborn skinfold measurements. South Asian women were younger (30.1 vs 31.8 years, P<0.001), their prepregnancy body mass index was lower (23.7 vs 26.2, P<0.0001) and gestational diabetes was substantially higher (21% vs 13%, P=0.005) compared with Whites. Among full-term newborns, South Asians had lower birthweight (3283 vs 3517 g, P=0.0001), had greater skinfold thickness (11.7 vs 10.6 mm; P=0.0001) and higher waist circumference (31.1 vs 29.9 cm, P=0.0001) compared with Whites. Risk factors for newborn skinfold thickness included South ...Continue Reading

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Dec 19, 2016·Clinical Endocrinology·Lisa C HudginsDaniel M Levine
Feb 21, 2019·Diabetes/metabolism Research and Reviews·Gang TianDongsheng Hu
Feb 7, 2020·JPEN. Journal of Parenteral and Enteral Nutrition·Emily NagelSara Ramel
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Aug 3, 2021·Reproductive Sciences·Nikita P JoshiChittaranjan S Yajnik

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