What are the current results of sutureless valves in high-risk aortic valve disease patients?

Interactive Cardiovascular and Thoracic Surgery
Amir H SepehripourThanos Athanasiou

Abstract

A best evidence topic was written according to a structured protocol. The question addressed was whether sutureless aortic valves have a clinical and haemodynamic benefit in high-risk patients with aortic valve disease. A total of 307 papers were found using the reported searches; of which, six represented the best evidence to answer the clinical question. The authors, date, journal, study type, population, main outcome measures and results are tabulated. The studies found analysed the outcomes of sutureless aortic valve implantation in high-risk patients undergoing aortic valve replacement. Reported measures included mortality; post-operative complications namely stroke, renal failure, endocarditis and bleeding; valve deployment, cardiopulmonary bypass (CPB) and aortic cross-clamp (ACC) times; echocardiographic assessment of paravalvular leaks (PVLs) and valve haemodynamics; and symptomatic functional class. Hospital mortality ranged between 3.1 and 12.5% and long-term mortality ranged between 3.1 and 10%. Incidence of PVL was found to be between 0.0 and 11%. Stroke was observed in 0.7%, renal failure in 3.1%, prosthetic valve endocarditis in 2.1-3.1% and major bleeding in 3.1%. The valve deployment time was 9-21 min, CPB time...Continue Reading

References

Aug 3, 2007·Interactive Cardiovascular and Thoracic Surgery·Joel DunningKevin Mackway-Jones
May 26, 2009·The Annals of Thoracic Surgery·Sven MartensMirko Doss
Jul 20, 2010·The Journal of Thoracic and Cardiovascular Surgery·Thierry AymardThierry Carrel
Aug 3, 2010·The Journal of Thoracic and Cardiovascular Surgery·Ingo BreitenbachWolfgang Harringer
Feb 24, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sven MartensThierry Carrel
Apr 9, 2011·The Journal of Thoracic and Cardiovascular Surgery·Willem FlamengBart Meuris
Jun 7, 2011·The New England Journal of Medicine·Craig R SmithUNKNOWN PARTNER Trial Investigators
May 1, 2012·The Annals of Thoracic Surgery·Thierry A FolliguetMalakh Shrestha

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Citations

Jun 1, 2013·General Thoracic and Cardiovascular Surgery·Hiroshi Furukawa, Kazuo Tanemoto
Feb 2, 2013·Current Opinion in Cardiology·Roberto LorussoAttilio Renzulli
May 10, 2015·Interactive Cardiovascular and Thoracic Surgery·Marco VolaAntoine Gerbay
Dec 3, 2014·The Journal of Thoracic and Cardiovascular Surgery·Eduard PermanyerRafael Llorens
Dec 14, 2017·Interactive Cardiovascular and Thoracic Surgery·Elisabet Berastegui GarcíaXavier Ruyra Baliarda
Sep 29, 2020·The Annals of Thoracic Surgery·J Mark ErfePatrick M McCarthy

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