What are the perspectives for ventilated tetraplegics? A French retrospective study of 108 patients with cervical spinal cord injury

Annals of Physical and Rehabilitation Medicine
A QuesnelE Verin

Abstract

Tetraplegic patients are often difficult to manage in intensive care units (ICU). The aim of our study was to calculate the incidence of patients in ICU with cervical spinal cord injury with special focus on tetraplegic patients on ventilation support and their future perspectives. This retrospective study included patients with cervical spinal cord injury in Upper Normandy, between 2002 and 2012. Data analyzed included age, sex, past medical history, date of onset of quadriplegia, level of neurological involvement, AIS grade, and ventilatory status. One hundred and eight patients were included (49.0 ± 21.1 years). The most common etiology was fall (50 patients [46.3%]). Incidence was calculated at 12.7 per one million inhabitants. Tracheotomy was performed in 40.7% of patients. Long-term mechanical ventilation was required for 6.5%. At the end of the study, 9 patients (9.6%) were permanently hospitalized, 61 patients (64.9%) had returned home but none of the four ventilated patients had been discharged. The conclusion of this work is that the future of highly tetraplegic patients is compromised, especially for those who remain reliant on mechanical ventilation.

References

Nov 24, 1999·Archives of Physical Medicine and Rehabilitation·M J DeVivoD P Lammertse
Sep 26, 2003·American Journal of Physical Medicine & Rehabilitation·Christopher Winslow, Julia Rozovsky
Aug 23, 2005·Accident; Analysis and Prevention·Peter J O'Connor
Nov 16, 2010·Respiratory Physiology & Neurobiology·Eric VerinThomas Similowski
Mar 1, 2011·Archives of Physical Medicine and Rehabilitation·Michael J DeVivo, Yuying Chen
Mar 26, 2013·Annals of Rehabilitation Medicine·Ji Cheol ShinSeo Yeon Yoon

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Citations

Mar 9, 2017·Breathe·David J BerlowitzJack Ross
Aug 17, 2018·BioMed Research International·Yan WangHaijun Teng
Nov 22, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Paseka M SerotoAdriaan J Vlok
Jan 16, 2020·Journal of Voice : Official Journal of the Voice Foundation·Felipe de Oliveira RodriguesLaura Davison Mangilli
Oct 16, 2018·Chest·Abdulghani SankariM Safwan Badr

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