What can we learn from gene expression profiling of mouse oocytes?

Reproduction : the Official Journal of the Society for the Study of Fertility
Toshio HamataniYasunori Yoshimura

Abstract

Mammalian ooplasm supports the preimplantation development and reprograms the introduced nucleus transferred from a somatic cell to confer pluripotency in a cloning experiment. However, the underlying molecular mechanisms of oocyte competence remain unknown. Recent advances in microarray technologies have allowed gene expression profiling of such tiny specimens as oocytes and preimplantation embryos, generating a flood of information about gene expressions. So, what can we learn from it? Here, we review the initiative global gene expression studies of mouse and/or human oocytes, focusing on the lists of maternal transcripts and their expression patterns during oogenesis and preimplantation development. Especially, the genes expressed exclusively in oocytes should contribute to the uniqueness of oocyte competence, driving mammalian development systems of oocytes and preimplantation embryos. Furthermore, we discuss future directions for oocyte gene expression profiling, including discovering biomarkers of oocyte quality and exploiting the microarray data for 'making oocytes'.

References

Sep 22, 1995·The Journal of Biological Chemistry·J Y NothiasM L DePamphilis
Nov 1, 1996·Fertility and Sterility·R J van KooijE R te Velde
May 7, 1998·Molecular Human Reproduction·J CohenS Willadsen
May 15, 1999·Human Reproduction·T TakeuchiG D Palermo
May 1, 2001·Theriogenology·D T Armstrong
Jul 4, 2001·Nature Reviews. Molecular Cell Biology·R Mendez, J D Richter
Sep 25, 2001·American Journal of Obstetrics and Gynecology·J Klein, M V Sauer
Dec 4, 2001·Journal of Reproductive Immunology·Jurrien Dean
May 2, 2002·Nature Genetics·Kam D DahlquistBruce R Conklin
Dec 10, 2002·Reproductive Biomedicine Online·Martin H JohnsonMargot L Day
Jan 15, 2003·Proceedings of the National Academy of Sciences of the United States of America·Nobuhiro SuzumoriMartin M Matzuk
Apr 26, 2003·Science·Kathleen H BurnsMartin M Matzuk
May 6, 2003·Science·Karin HübnerHans R Schöler
Dec 24, 2003·PLoS Biology·Alexei A SharovMinoru S H Ko
Jan 16, 2004·Developmental Cell·Toshio HamataniMinoru S H Ko
Mar 25, 2004·Reproductive Biomedicine Online·Mercedes G BermúdezNury M Steuerwald
May 20, 2004·Human Molecular Genetics·Anthony T DobsonRenee A Reijo Pera
Jul 30, 2004·Developmental Biology·Fanyi ZengRichard M Schultz
Aug 20, 2004·Human Molecular Genetics·Toshio HamataniMinoru S H Ko
Dec 14, 2005·Biochemical and Biophysical Research Communications·Steven Shoei-Lung LiSher Singh

❮ Previous
Next ❯

Citations

Jan 23, 2009·The Journal of Biological Chemistry·Aïcha MetchatElisabeth S Christians
Jan 20, 2009·Human Reproduction Update·I AdriaensP Jacquet
Mar 18, 2010·BMC Research Notes·Mark de JongTimo M Breit
Jun 22, 2010·The Journal of Reproduction and Development·Ken-Ichiro ABEFugaku AOKI
Nov 16, 2013·Molecular Human Reproduction·Rémi Labrecque, Marc-André Sirard
Jan 25, 2014·Reproduction : the Official Journal of the Society for the Study of Fertility·Kouji KomatsuFumitaka Kikkawa
Jul 14, 2010·Animal Reproduction Science·Tomoko AmanoKazuya Matsumoto
Jan 20, 2009·Theriogenology·M G Katz-JaffeD K Gardner
Dec 6, 2011·Molecular Reproduction and Development·Patrizia VitulloCorrado Spadafora
Dec 19, 2012·Theriogenology·Xiaofang DingHonggang Li
Oct 31, 2016·Biochemical and Biophysical Research Communications·Moein FarshchianAhmad Reza Bahrami
Sep 29, 2012·Biology of Reproduction·Junaid KashirKevin Coward
Jan 1, 2012·Genes·Aurora Ruiz-HerreraMontserrat Garcia-Caldés

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.