What do we know about homocysteine and exercise? A review from the literature

Clinical Chemistry and Laboratory Medicine : CCLM
Beatriz Maroto-SánchezMarcela González-Gross

Abstract

High total homocysteine (tHcy) concentrations contribute to an increased risk of cardiovascular diseases and neurodegenerative disorders. Several investigations have focused on the effect of exercise on tHcy concentrations, but results remain controversial. The differences among the methodologies in the investigations make difficult the interpretation of results. This review differentiates the effects of exercise on tHcy and establishes the relation with the implicated biomarkers on tHcy metabolism related to exercise. The electronic database MEDLINE (http://www.ncbi.nlm.nih.gov) was used for searching studies published between years 2002 and 2015. 'Homocysteine', 'Training ', 'Exercise', 'Physical Activity' as well as combinations out of these terms were entered in the database. Articles were grouped in: 1) Acute effect of exercise on tHcy, 2) chronic exercise and tHcy, 3) relationship of physical activity (PA) level and cardiorespiratory fitness with tHcy, and 4) biomarkers related to tHcy and exercise. From a total of 30 articles, most of the studies analyzing the acute effect of exercise showed an increase on tHcy concentrations. Studies analyzing the chronic effect on tHcy concentrations showed contradictory results and no...Continue Reading

References

Oct 4, 1995·JAMA : the Journal of the American Medical Association·C J BousheyA G Motulsky
Feb 12, 1998·The American Journal of Clinical Nutrition·O NygårdS E Vollset
Aug 12, 1999·Seminars in Thrombosis and Hemostasis·S C GubaL M Fink
Jun 29, 2000·The American Journal of Clinical Nutrition·N K FukagawaB O'Rourke
Mar 20, 2001·International Journal of Sport Nutrition and Exercise Metabolism·M J Gibala
Oct 5, 2002·The Journal of Clinical Endocrinology and Metabolism·Harpal S RandevaGordana M Prelevic
Nov 16, 2002·Medicina clínica·Marcela González-GrossManuel J Castillo
Nov 8, 2003·Preventive Cardiology·Kevin R VincentDavid T Lowenthal
Dec 6, 2003·Clinical Chemistry and Laboratory Medicine : CCLM·Markus HerrmannWolfgang Herrmann
Oct 12, 2004·Preventive Medicine·Glen E DuncanPeter W Stacpoole
May 6, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·A S RousseauI Margaritis
May 6, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·J T RealR Carmena
Jan 10, 2006·The American Journal of Clinical Nutrition·Lori M SteadRené L Jacobs
Oct 4, 2006·European Journal of Applied Physiology·Tomohiro OkuraClaude Bouchard
Dec 2, 2006·International Journal of Sport Nutrition and Exercise Metabolism·Lanae M Joubert, Melinda M Manore
Feb 7, 2007·Archives of Pediatrics & Adolescent Medicine·Jonatan R RuizManuel J Castillo
Mar 16, 2007·Annals of Nutrition & Metabolism·Nihal GelecekOmer Kozan
Jun 9, 2007·Scandinavian Journal of Medicine & Science in Sports·E UntM Zilmer
Jun 22, 2007·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Salvatore SotgiaAngelo Zinellu
Jul 27, 2007·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Anthony S Wierzbicki
Oct 11, 2008·Medicine and Science in Sports and Exercise·Lanae M Joubert, Melinda M Manore
Oct 15, 2008·European Journal of Applied Physiology·Manuela Di SantoloSabina Cauci
Jul 2, 2009·Medicine and Science in Sports and Exercise·Rafael VentaNicolás Terrados
Mar 12, 2011·European Journal of Applied Physiology·Rafael DeminiceAlceu Afonso Jordao
Feb 26, 2013·Journal of the International Society of Sports Nutrition·Jorge Molina-LópezElena Planells
Aug 24, 2013·International Archives of Medicine·Franciele Marques VanderleiCelso Ferreira
Apr 24, 2014·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Jeong Kyu ChoiSang Mo Kwon

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Citations

Nov 26, 2016·European Journal of Preventive Cardiology·Cédric GubelmannPedro Marques-Vidal
Sep 25, 2019·PloS One·Jose D SantotoribioMaria J Sanchez Del Pino
Jul 25, 2019·European Review of Aging and Physical Activity : Official Journal of the European Group for Research Into Elderly and Physical Activity·Fabian HeroldNotger G Müller
Sep 29, 2018·Amino Acids·Beatriz Maroto-SánchezCiriaco Carru
Feb 2, 2021·Journal of Diabetes and Metabolic Disorders·Alexandre de Souza E SilvaMaria Paula Gonçalves da Mota
Apr 20, 2021·Molecular Genetics and Metabolism Reports·Aurel T TankeuChristel Tran

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