What do we know about quality of life in dementia? A review of the emerging evidence on the predictive and explanatory value of disease specific measures of health related quality of life in people with dementia

International Journal of Geriatric Psychiatry
S BanerjeeMegan del Valle

Abstract

Given its complexity, there is growing consensus on the need to measure patient-rated broad outcomes like health-related quality of life (HRQL) as well as discrete functions like cognition and behaviour in dementia. This review brings together current data on the distribution, determinants and course of HRQL in dementia to investigate the predictive and explanatory value of measures of HRQL in people with dementia. A systematic review of papers in English published up to October 2007 to identify data on the use of disease-specific measures of HRQL in dementia. There are no clear or consistent associations between socio-demographic variables and HRQL. There is no convincing evidence that lower cognition or greater activity limitation is associated with lower HRQL. There is a strong suggestion that depression is consistently associated with decreased HRQL in dementia. However, the magnitude of the associations observed is moderate only and the proportion of variance explained is low suggesting that depression and HRQL are different constructs. We currently know almost nothing about the natural history of HRQL in dementia or what attributes or interventions promote or inhibit HRQL life for people with dementia. While in other illn...Continue Reading

References

Nov 1, 1978·The British Journal of Psychiatry : the Journal of Mental Science·A H Pattie, C J Gilleard
Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Jan 1, 1982·Journal of Psychiatric Research·J A YesavageV O Leirer
Aug 1, 1993·The Gerontologist·E C Clipp, L K George
Jul 2, 1999·Social Science & Medicine·G L Albrecht, P J Devlieger
Feb 19, 2000·International Journal of Geriatric Psychiatry·T González-SalvadorC Steele
May 11, 2002·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Michel SilberfeldGary Naglie
May 22, 2002·Psychosomatic Medicine·Rebecca G LogsdonLinda Teri
Apr 4, 2003·International Journal of Geriatric Psychiatry·Constantine G LyketsosPeter Rabins
May 13, 2003·Health and Quality of Life Outcomes·Rebecca E Ready, Brian R Ott
Aug 12, 2003·Schizophrenia Bulletin·Lon S SchneiderPierre N Tariot
Sep 2, 2003·The British Journal of Psychiatry : the Journal of Mental Science·Aimee SpectorMartin Orrell
May 8, 2004·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·N Yamamoto-MitaniK Kamata
Dec 2, 2004·Dementia and Geriatric Cognitive Disorders·Kristin Martin-CookMyron F Weiner
Feb 18, 2005·International Journal of Geriatric Psychiatry·Amber SelwoodMartin Orrell
Apr 27, 2005·International Journal of Geriatric Psychiatry·Martin OrrellBob Woods
Jul 19, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Teake P EttemaMiel W Ribbe
Aug 27, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Sherrill Evans, Peter Huxley
Oct 19, 2005·The Gerontologist·Sheryl ZimmermanRichard Schulz
Oct 19, 2005·The Gerontologist·Philip D SloaneJohn S Preisser
Oct 19, 2005·The Gerontologist·Sheryl ZimmermanDebra Dobbs
Dec 3, 2005·International Journal of Geriatric Psychiatry·Philippe ThomasJean-Pierre Clément
Jan 18, 2006·International Journal of Geriatric Psychiatry·Jong-Ling Fuh, Shuu-Jiun Wang
Jan 20, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·S BanerjeeM Knapp
May 2, 2006·The British Journal of Psychiatry : the Journal of Mental Science·J HoeM Orrell
Jun 2, 2006·The British Journal of Psychiatry : the Journal of Mental Science·Martin KnappMartin Orrell
Jun 17, 2006·Aging & Mental Health·B WoodsM Orrell
Sep 7, 2006·International Journal of Geriatric Psychiatry·Asmus VogelGunhild Waldemar
Sep 9, 2006·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Quincy M SamusConstantine G Lyketsos
Oct 13, 2006·The New England Journal of Medicine·Lon S SchneiderUNKNOWN CATIE-AD Study Group
Oct 18, 2006·International Journal of Geriatric Psychiatry·Teake P EttemaMiel W Ribbe
Nov 30, 2006·International Journal of Geriatric Psychiatry·Carla J M Schölzel-DorenbosRose-Marie Dröes
Dec 1, 2006·Alzheimer Disease and Associated Disorders·Marian B PattersonUNKNOWN Alzheimer's Disease Cooperative Study Group
Jan 24, 2007·International Journal of Geriatric Psychiatry·Sube BanerjeeJoanna Murray
Mar 10, 2007·International Psychogeriatrics·Peter V Rabins, Betty S Black
Mar 31, 2007·International Journal of Geriatric Psychiatry·Martin OrrellDavid Challis
May 16, 2007·International Journal of Geriatric Psychiatry·Pierre MissottenOvide Fontaine
Jul 5, 2007·BMC Medical Research Methodology·Rob McCarneyPeter Fisher

❮ Previous
Next ❯

Citations

Nov 1, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Betty S BlackQuincy M Samus
Sep 7, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Peter MakaiAnna P Nieboer
Jul 28, 2012·Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Österreichischer Nervenärzte und Psychiater·Elisabeth M WeissEberhard A Deisenhammer
Mar 8, 2013·International Journal of Nursing Studies·Hanneke C BeerensJan P H Hamers
May 8, 2010·International Psychogeriatrics·Ramona Lucas-CarrascoJuana Gómez-Benito
Mar 2, 2012·International Psychogeriatrics·Richard TriggRachel Elliman
Dec 12, 2012·Aging & Mental Health·Helena BárriosAlexandre de Mendonça
Feb 8, 2011·Alzheimer Disease and Associated Disorders·Ramona Lucas-CarrascoJaume March
Oct 18, 2011·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S Voigt-RadloffM Hüll
May 17, 2012·BMJ : British Medical Journal·Els J MeeuwsenMarcel G M Olde Rikkert
Jul 16, 2011·Dementia and Geriatric Cognitive Disorders·Maria L BarcaGeir Selbæk
Aug 19, 2011·Dementia and Geriatric Cognitive Disorders·Kosuke NakanishiShutaro Nakaaki
Aug 3, 2012·Dementia and Geriatric Cognitive Disorders·Froydis Kristine BruvikKnut Engedal
Jan 2, 2013·Dementia and Geriatric Cognitive Disorders Extra·Pascalle R BosboomChristopher Beer
Jan 24, 2013·Therapeutic Advances in Chronic Disease·Enrico Mossello, Elena Ballini
Sep 27, 2012·Health and Quality of Life Outcomes·Carla J M Schölzel-DorenbosPaul F M Krabbe
Jul 13, 2012·Alzheimer's Research & Therapy·Rianne M van der LindeCarol Brayne
Dec 10, 2013·International Journal of Environmental Research and Public Health·Elisabeth Wiken TeleniusAstrid Bergland
May 24, 2014·Clinical Interventions in Aging·Nicola GatesMaria A Fiatarone Singh
Aug 27, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Johannes GräskeKarin Wolf-Ostermann
Jul 23, 2013·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Christian BakkerRaymond T C M Koopmans
Aug 8, 2014·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Pascalle R Bosboom, Osvaldo P Almeida
Aug 1, 2015·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Armin von GuntenKarl Überla
Jan 17, 2016·Social Science & Medicine·Juan TellezCatherine Le Galès
Jul 31, 2013·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Laura N GitlinWalter W Hauck
Apr 10, 2013·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Katharina GeschkeArmin Scheurich
Apr 1, 2011·Journal of the American Medical Directors Association·Henrike J SchoutenRob J van Marum
Nov 13, 2015·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Sarah CinesStephanie Cosentino
Aug 28, 2010·Journal of Psychosocial Nursing and Mental Health Services·Julianne Loge, Jeanne M Sorrell
Dec 17, 2014·Health and Quality of Life Outcomes·Johannes GräskeKarin Wolf-Ostermann
Apr 19, 2011·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Christopher R CarpenterJohn C Morris
Jul 13, 2013·Journal of Psychiatric and Mental Health Nursing·N McCrae, J Bloomfield
Nov 9, 2010·Journal of the American Geriatrics Society·Zachary CordnerBetty S Black
Jul 8, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Pablo Martinez-MartinAnette Schrag

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