What happens when Trypanosoma brucei leaves Africa.

Trends in Parasitology
Robert E JensenPaul T Englund

Abstract

Julius Lukes and co-workers evaluated the evolutionary origin of Trypanosoma equiperdum and Trypanosoma evansi, parasites that cause horse and camel diseases. Although similar to T. brucei, the sleeping-sickness parasite, these trypanosomes do not cycle through the tsetse fly and have been able to spread beyond Africa. Transmission occurs sexually, or via blood-sucking flies or vampire bats. They concluded that these parasites, which resemble yeast petite mutants, are T. brucei sub-species, which have evolved recently through changes in mitochondrial DNA.

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Citations

Dec 17, 2009·Antimicrobial Agents and Chemotherapy·Sonya C Tang, Theresa A Shapiro
Dec 29, 2010·PLoS Pathogens·Arnab Roy ChowdhuryPaul T Englund
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Oct 26, 2010·Molecular Microbiology·Marina CristoderoAndré Schneider
Apr 8, 2015·Mutation Research·Gonzalo GreifFernando Alvarez-Valin
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Oct 23, 2014·The Journal of Biological Chemistry·Paul T Englund
Aug 17, 2021·Microbial Genomics·Guy OldrieveKeith R Matthews

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