What has the baboon to offer as a model of experimental ischemia?

European Heart Journal
L H OpieW F Lubbe


The greatest advantage of the baboon model is the phylogenetic closeness of the animal to man which may be of considerable importance when dealing with receptor-related events and with drug-specific therapy. The major disadvantage is the difficulty of dealing with awake baboons and the absence of any adequate model for coronary artery spasm.


Jan 1, 1985·Molecular Aspects of Medicine·J H BottingM J Walker
Jan 11, 2001·Journal of Pharmacological and Toxicological Methods·A H SmithD R Knight

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