PMID: 16639220Apr 28, 2006Paper

What is the best method for assessing the rate of wound healing? A comparison of 3 mathematical formulas

Advances in Skin & Wound Care
Rebecca L Jessup

Abstract

To identify and evaluate current mathematical formulas used to assess the rate of wound healing. MEDLINE, CINAHL, and Cochrane Systematic Review databases, from 1965 to 2004. Papers selected for the study met the following inclusion criteria: (1) participants had chronic venous, neuropathic, pressure, or ischemic wounds; (2) the wounds were objectively measured; and (3) the investigators described and used an objective measurement of wound healing rate, either as an absolute reduction in area over time, a percentage change, or a linear advancement of wound edge. Papers were excluded if they were (1) not written in English, (2) duplicated from other sources, or (3) unpublished. In clinical trials, measurement of the rate of wound healing over time by using the equation for the linear advancement of wound margins toward the center of the wound controls for confounding introduced by differing baseline ulcer sizes and shapes. Use of this assessment method after 4 weeks of healing may prove to be of value in predicting time to complete healing. Further research is required to develop standard healing rates for wounds of different etiologies.

References

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Citations

Jan 2, 2007·Advances in Skin & Wound Care·Denis OkanGary Sibbald
Dec 20, 2008·Advances in Skin & Wound Care·Robert RennertHarold Brem
May 19, 2011·Annals of Plastic Surgery·Véronique St-SuperyAndreas Nikolis
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Jun 9, 2014·Burns : Journal of the International Society for Burn Injuries·Shi-Yuan SheuChun-Hsu Yao
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Jul 25, 2012·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Nick SantamariaAlexandra Gorelik
Aug 14, 2013·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Alessandro Melo DeanaCristiane Miranda França
Jan 20, 2010·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Jaymie PanuncialmanVincent Falanga
May 25, 2010·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Elisabeth S PapazoglouMichael S Weingarten
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Jan 7, 2020·Advances in Wound Care·Caroline E Fife, Susan D Horn
Nov 30, 2006·Advances in Skin & Wound Care·Carly KirshenR Gary Sibbald

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