What Makes the Human Brain Human?

Neuron
Robert F Hevner

Abstract

Which elements of the genome endow human brains with the capacity for heightened cognitive abilities? In this issue of Neuron, Namba et al. (2020) find that ARHGAP11B, a human-specific gene, augments cerebral cortex expansion by regulating metabolic pathways in mitochondria.

References

Feb 19, 2013·Trends in Neurosciences·Karl ZillesKatrin Amunts
Mar 22, 2014·Nature Reviews. Neuroscience·Tao Sun, Robert F Hevner
Aug 10, 2016·Proceedings of the National Academy of Sciences of the United States of America·Mariana GabiSuzana Herculano-Houzel
Mar 17, 2017·Annual Review of Biomedical Engineering·Lifeng YangDeepak Nagrath
Jan 6, 2019·Nature Reviews. Neuroscience·Cristina Llinares-Benadero, Víctor Borrell
Nov 13, 2019·Proceedings of the National Academy of Sciences of the United States of America·Stefano BertoGenevieve Konopka

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