No abstract listed.
The EPIC Project: rationale and study design. European Prospective Investigation into Cancer and Nutrition
The UK Biobank sample handling and storage protocol for the collection, processing and archiving of human blood and urine
Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology
Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
Completeness and diagnostic validity of recording acute myocardial infarction events in primary care, hospital care, disease registry, and national mortality records: cohort study
Prevalence and characteristics of probable major depression and bipolar disorder within UK biobank: cross-sectional study of 172,751 participants
The use of biospecimens in population-based research: a review of the National Cancer Institute's Division of Cancer Control and Population Sciences grant portfolio
Understanding the impact of pre-analytic variation in haematological and clinical chemistry analytes on the power of association studies
Low birth weight and features of neuroticism and mood disorder in 83 545 participants of the UK Biobank cohort
Investigating the association between tinnitus severity and symptoms of depression and anxiety, while controlling for neuroticism, in a large middle-aged UK population
Leg length is associated with lower values of inflammatory markers in older Chinese: The Guangzhou Biobank Cohort Study
Unraveling the role for genetics in enabling precision prescription for weight loss-scaling up for success
Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics
Cardiometabolic disease and features of depression and bipolar disorder: population-based, cross-sectional study
Blood pressure in relation to general and central adiposity among 500 000 adult Chinese men and women
Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)
5 year mortality predictors in 498,103 UK Biobank participants: a prospective population-based study
Season and outdoor temperature in relation to detection and control of hypertension in a large rural Chinese population
Sex hormones and risk of breast cancer in premenopausal women: a collaborative reanalysis of individual participant data from seven prospective studies
Size matters: how population size influences genotype-phenotype association studies in anonymized data
Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation
Accuracy of Patient Self-Report of Stroke: A Systematic Review from the UK Biobank Stroke Outcomes Group
What Potential Donors in Research Biobanking Want to Know: A Large Population Study of the Italian Twin Registry
Patterns and socio-demographic correlates of domain-specific physical activities and their associations with adiposity in the China Kadoorie Biobank study
Achievements, challenges, and future perspectives of epidemiologic research in restless legs syndrome (RLS)
Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published Studies
Optical Coherence Tomography in the UK Biobank Study - Rapid Automated Analysis of Retinal Thickness for Large Population-Based Studies
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease
Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits
Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis
UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age
Can large surveys conducted on highly selected populations provide valid information on the epidemiology of common health conditions? An analysis of UK Biobank data on musculoskeletal pain
The Korean Heart Study: rationale, objectives, protocol, and preliminary results for a new prospective cohort study of 430,920 men and women
Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease
Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population
Associations Between Diabetes and Both Cardiovascular Disease and All-Cause Mortality Are Modified by Grip Strength: Evidence From UK Biobank, a Prospective Population-Based Cohort Study
Dietary Intake of High-Protein Foods and Other Major Foods in Meat-Eaters, Poultry-Eaters, Fish-Eaters, Vegetarians, and Vegans in UK Biobank
Genetic identification of a common collagen disease in puerto ricans via identity-by-descent mapping in a health system
Harmonising data on the correlates of physical activity and sedentary behaviour in young people: Methods and lessons learnt from the international Children's Accelerometry database (ICAD)
Associations of coffee genetic risk scores with consumption of coffee, tea and other beverages in the UK Biobank
Assessing the causal association between 25-hydroxyvitamin D and the risk of oral and oropharyngeal cancer using Mendelian randomization
The Impact of Glycated Hemoglobin (HbA1c ) on Cardiovascular Disease Risk: A Mendelian Randomization Study Using UK Biobank
Is smoking heaviness causally associated with alcohol use? A Mendelian randomization study in four European cohorts.
Vitamin D and Inflammatory Bowel Disease: Mendelian Randomization Analyses in the Copenhagen Studies and UK Biobank
Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality: UK Biobank cohort study of 479 054 men and women
How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1,937,360 People
Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor
An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings
Circulating Phylloquinone Concentrations and Risk of Type 2 Diabetes: A Mendelian Randomization Study
The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study.
Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference
The Combination of Physical Activity and Sedentary Behaviors Modifies the Genetic Predisposition to Obesity
The association of grip strength with health outcomes does not differ if grip strength is used in absolute or relative terms: a prospective cohort study
Inter-individual differences in human brain structure and morphology link to variation in demographics and behavior
Comparison of Conventional Lipoprotein Tests and Apolipoproteins in the Prediction of Cardiovascular Disease: Data from UK Biobank
Correlates of Hearing Aid Use in UK Adults: Self-Reported Hearing Difficulties, Social Participation, Living Situation, Health, and Demographics
Associations Between Sedentary Behaviors and Cognitive Function: Cross-Sectional and Prospective Findings From the UK Biobank
Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease
Hearing Difficulties and Tinnitus in Construction, Agricultural, Music, and Finance Industries: Contributions of Demographic, Health, and Lifestyle Factors
Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study
Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort study and individual participant meta-analysis
Identification of patients with atrial fibrillation: a big data exploratory analysis of the UK Biobank.
Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants
Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease
Association Between Walking Pace and Stroke Incidence: Findings From the UK Biobank Prospective Cohort Study.
Thyroid Function Affects the Risk of Stroke via Atrial Fibrillation: A Mendelian Randomization Study.
The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population.
The causal effects of health conditions and risk factors on social and socioeconomic outcomes: Mendelian randomization in UK Biobank.
Vitamin D Status and Risk of All-Cause and Cause-Specific Mortality in a Large Cohort: Results From the UK Biobank.
Investigating pleiotropic effects of statins on ischemic heart disease in the UK Biobank using Mendelian randomisation
Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank
From paediatrics to geriatrics: a life course perspective on the MRC National Survey of Health and Development
Interactions of coffee consumption and postmenopausal hormone use in relation to breast cancer risk in UK Biobank
Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis.
Causal Factors for Knee, Hip, and Hand Osteoarthritis: A Mendelian Randomization Study in the UK Biobank
Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study
The Associations of Diuretics and Laxatives Use with Cardiovascular Mortality. An Individual Patient-Data Meta-analysis of Two Large Cohort Studies
A multivariable Mendelian randomization to appraise the pleiotropy between intelligence, education, and bipolar disorder in relation to schizophrenia.
Cohort studies with low baseline response may not be generalisable to populations with different exposure distributions
Associations of discretionary screen time with mortality, cardiovascular disease and cancer are attenuated by strength, fitness and physical activity: findings from the UK Biobank study
The impact of confounding on the associations of different adiposity measures with the incidence of cardiovascular disease: a cohort study of 296 535 adults of white European descent
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases
Hematological parameters and prevalence of anemia in white and British Indian vegetarians and nonvegetarians in the UK Biobank
Factors associated with potentially serious incidental findings and with serious final diagnoses on multi-modal imaging in the UK Biobank Imaging Study: A prospective cohort study
Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study
Persistent Underutilization of BRCA1/2 Testing Suggest the Need for New Approaches to Genetic Testing Delivery
Age at puberty and accelerometer-measured physical activity: Findings from two independent UK cohorts.
High-Throughput Sequencing in Respiratory, Critical Care, and Sleep Medicine Research. An Official American Thoracic Society Workshop Report
Cognitive ability and risk of death from lower respiratory tract infection: findings from UK Biobank
Harmonization of the Health and Risk Factor Questionnaire data of the Canadian Partnership for Tomorrow Project: a descriptive analysis
Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour
Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans.
Opportunities, challenges and expectations management for translating biobank research to precision medicine
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
Genotype-environment interaction on human cognitive function conditioned on the status of breastfeeding and maternal smoking around birth
Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants
Anthropometric and physiologic characteristics in white and British Indian vegetarians and nonvegetarians in the UK Biobank
The impact of glycated hemoglobin on risk of hypertension: a Mendelian randomization study using UK Biobank.
Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses.
Can increasing years of schooling reduce type 2 diabetes (T2D)?: Evidence from a Mendelian randomization of T2D and 10 of its risk factors
The effects of age at menarche and first sexual intercourse on reproductive and behavioural outcomes: A Mendelian randomization study.
The prevalence of co-morbidities and their impact on physical activity in people with inflammatory rheumatic diseases compared with the general population: results from the UK Biobank
Reference range of liver corrected T1 values in a population at low risk for fatty liver disease-a UK Biobank sub-study, with an appendix of interesting cases
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations
Genotype-covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model
Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants.
Identifying environmental risk factors for inflammatory bowel diseases: a Mendelian randomization study.
Individual and combined associations between cardiorespiratory fitness and grip strength with common mental disorders: a prospective cohort study in the UK Biobank.
Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank.
A phenome-wide association study of 26 mendelian genes reveals phenotypic expressivity of common and rare variants within the general population.
Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations.
Effects of Thyroid Status on Regional Brain Volumes: A Diagnostic and Genetic Imaging Study in UK Biobank.
The National Cancer Institute Cohort Consortium: An International Pooling Collaboration of 58 Cohorts from 20 Countries
Circulating Insulin-like Growth Factor-I Concentrations and Risk of 30 Cancers: Prospective Analyses in UK Biobank.
Family Study Designs Informed by Tumor Heterogeneity and Multi-Cancer Pleiotropies: The Power of the Utah Population Database
Combined association of general and central obesity with incidence and mortality of cancers in 22 sites.
Pre-diagnostic circulating concentrations of insulin-like growth factor-1 and risk of COVID-19 mortality: results from UK Biobank.
Frailty, sarcopenia, cachexia and malnutrition as comorbid conditions and their associations with mortality: a prospective study from UK Biobank.
Practice of reporting social characteristics when describing representativeness of epidemiological cohort studies - A rationale for an intersectional perspective.
Circulating lipids and glioma risk: results from the UK Biobank, Nurses' Health Study, and Health Professionals Follow-Up Study.
Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile.
Vegetarians, fish, poultry, and meat-eaters: who has higher risk of cardiovascular disease incidence and mortality? A prospective study from UK Biobank.
MR-LDP: a two-sample Mendelian randomization for GWAS summary statistics accounting for linkage disequilibrium and horizontal pleiotropy.
Associations of six adiposity-related markers with incidence and mortality from 24 cancers-findings from the UK Biobank prospective cohort study.
Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort study.
The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.
Development and Validation of Risk Scores for All-Cause Mortality for a Smartphone-Based "General Health Score" App: Prospective Cohort Study Using the UK Biobank.
Approaches to minimising the epidemiological impact of sources of systematic and random variation that may affect biochemistry assay data in UK Biobank
Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study.
Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease
Lipoprotein(a) and cardiovascular disease: prediction, attributable risk fraction, and estimating benefits from novel interventions.
Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study.
Associations of sleep duration and quality with incident cardiovascular disease, cancer, and mortality: a prospective cohort study of 407,500 UK biobank participants.
The joint association of sarcopenia and frailty with incidence and mortality health outcomes: A prospective study.
Identification of a Novel Genetic Marker for Risk of Degenerative Rotator Cuff Disease Surgery in the UK Biobank.
Comparison and impact of COVID-19 for patients with cancer: a survival analysis of fatality rate controlling for age, sex and cancer type.
Associations Between Macronutrients From Different Dietary Sources and Serum Lipids in 24 639 UK Biobank Study Participants.
Association of genetically predicted serum estradiol with risk of thromboembolism in men: A mendelian randomization study.
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
STING Receptor Agonists
Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.
Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.
Spatio-Temporal Regulation of DNA Repair
DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.
Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.
Hereditary Sensory Autonomic Neuropathy
Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.
Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.
Neural Activity: Imaging
Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.
Applications of Molecular Barcoding
The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.