PMID: 9650361Jul 3, 1998Paper

What was not included in the recommendations for the diagnosis and therapy of hyperlipoproteinemia in childhood

Casopís lékar̆ů c̆eských
M SamánekR Ceska

Abstract

Screening and treatment of hyperlipidaemia should be the concern of paediatricians. This is suggested by the finding of fatty streaks and other atheromatic changes in children. The authors prefer selective to nationwide screening in children who have close relatives with coronary heart disease or cerebral haemorrhage before the age of 55 years in men and 65 years in women or elevated total cholesterol levels. In case of repeated total cholesterol levels of 4.4-5.2 mmol/l the authors recommend annual, in case of levels above 5.2 mmol/l 3-6 month intervals between examinations. The authors found values above 5.2 mmol/l in one quarter of otherwise healthy children. In addition to the hyperlipidaemic theory there is the infectious theory of development of atherosclerosis and the theory of programming of coronary heart disease during pregnancy. By dietary and lifestyle provisions it is possible to reduce hyperlipidaemia in the great majority of children. In boys above 10 years and girls above 20 years resins are indicated if the total cholesterol level is above 8 mmol/l.

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