Wheat pathogenesis-related proteins of class 4 have ribonuclease activity

FEBS Letters
Carlo CaporaleCarla Caruso

Abstract

We have demonstrated that wheatwin1, a wheat pathogenesis-related protein of class 4 (PR4), has ribonuclease activity. Both native and recombinant proteins hydrolyse RNA from wheat coleoptils and have antifungal activity. Sepharose-bound wheatwin1 is able to interact with either wheat or Fusarium culmorum RNA. 3D modelling studies showed that, like ribonucleases A and T1, the action mechanism should involve two His residues, an Arg residue and an Asp residue.

References

Sep 22, 1992·Biochemistry·S Ludvigsen, F M Poulsen
Dec 5, 1993·Journal of Molecular Biology·A Sali, T L Blundell
Jan 1, 1996·Journal of Protein Chemistry·C CarusoV Buonocore
Dec 1, 1996·Nature Structural Biology·M GajhedeM D Spangfort
Mar 22, 2000·DNA Sequence : the Journal of DNA Sequencing and Mapping·C CarusoV Buonocore
Oct 12, 2001·Journal of Protein Chemistry·C CarusoC Caporale
Nov 28, 2001·Protein Expression and Purification·C CarusoV Buonocore
Jun 25, 2002·Journal of Molecular Biology·Jacek BiesiadkaMariusz Jaskolski
Mar 15, 2003·Journal of Molecular Modeling·Carlo CaporaleCarla Caruso
Dec 19, 2003·Biochemical and Biophysical Research Communications·Fang WuWeimin Gong
May 1, 2002·Molecular Plant Pathology·Anders B ChristensenHans Thordal-Christensen

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Citations

Jun 1, 2010·Journal of Experimental Botany·Maria Angeles Guevara-MoratoMaria Teresa Serra
Jan 5, 2011·Journal of Experimental Botany·S ProiettiC Caruso
Apr 11, 2006·Annual Review of Phytopathology·L C van LoonC M J Pieterse
Aug 10, 2006·Biological Chemistry·Laura BertiniCarla Caruso
Aug 4, 2009·FEBS Letters·Laura BertiniCarla Caruso
Oct 1, 2011·Journal of Plant Physiology·Nili WangLizhong Xiong
Apr 27, 2016·Plant Signaling & Behavior·Hongwei LiuPeer M Schenk
Jun 15, 2007·Annals of Botany·Abelmon S GesteiraJúlio C M Cascardo
Oct 9, 2013·Acta Crystallographica. Section D, Biological Crystallography·Joëlle HuetAlexandre Wohlkönig
Jun 4, 2020·Probiotics and Antimicrobial Proteins·Ping-Ping TianYuan-Sen Hu
Jan 23, 2019·Frontiers in Plant Science·Flávia P FrancoMarcio C Silva-Filho
Jul 6, 2018·Genes·Ethan J AndersenMadhav P Nepal
Sep 28, 2021·Frontiers in Plant Science·Lorhenn Bryanda Lemes MaiaMarcio C Silva-Filho

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