Wheel running in female C57BL/6J mice: impact of oestrus and dietary fat and effects on sleep and body mass

International Journal of Obesity : Journal of the International Association for the Study of Obesity
L BasterfieldJ C Mathers

Abstract

To examine the impact of two diets differing in fat content and of wheel-running exercise on body mass. A total of 32 female C57BL/6J mice were assigned to either a high-fat (HF, 41% of dietary energy as fat) or low-fat (LF, 11% of dietary energy as fat) diet (16 per diet, individually housed). Eight mice from each diet group were housed with running wheels. Non-running mice were housed in similar cages, without wheels. Total cage activity (including non-exercise physical activity +wheel running) and sleep time were also measured using an infra-red-sensing device. Oestrus stage of the wheel-running mice was assessed daily for 17 days. After 8 weeks, HF mice were significantly heavier than LF mice (P=0.004), but there was no detectable difference in body fat mass. Wheel-running mice tended to have a lower body mass than non-running controls (P=0.056). Voluntary cage activity was greater in LF control mice than HF control mice, and in wheel-running mice compared with non-wheel-running mice. HF control mice slept more than LF control mice. Stage of oestrus was significantly correlated with running distance, with mice running farthest in the immediate preoestrus phase and least immediately after oestrus. This study shows that HF di...Continue Reading

References

Aug 1, 1989·Physiology & Behavior·H G Anantharaman-Barr, J Decombaz
Apr 15, 2000·Nature·P G Kopelman
Nov 9, 2001·Behavior Genetics·A M BronikowskiT Garland
Jan 9, 2003·JAMA : the Journal of the American Medical Association·Kevin R FontaineDavid B Allison
May 22, 2003·JAMA : the Journal of the American Medical Association·Finlay A McAlisterDouglas G Altman
Aug 21, 2004·American Journal of Physiology. Heart and Circulatory Physiology·John P KonhilasLeslie A Leinwand
Sep 24, 2004·Physiological Genomics·J Timothy LightfootSteven R Kleeberger
Dec 1, 2004·The Journal of Nutrition·Alexandra FunkatSofianos Andrikopoulos
Apr 23, 2005·Science·Fred W TurekJoseph Bass
Apr 28, 2005·Physiological Genomics·Michael J TurnerJ Timothy Lightfoot
Sep 15, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·I Bartol-MunierE Challet
Dec 13, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·J P De BonoK M Channon
Dec 20, 2005·Physiology & Behavior·Joe B JenkinsJidong Fang
Sep 21, 2006·Physiological Genomics·Allan I PackLuanne L Peters
Feb 6, 2007·Medicine and Science in Sports and Exercise·Jeffrey F GorzekDawn A Lowe
Mar 1, 2007·Sleep·J Richard JenningsStephen B Manuck
Nov 7, 2007·Cell Metabolism·Akira KohsakaJoseph Bass
Nov 27, 2007·Journal of Sleep Research·Karen A WatersLouise A Baur
Dec 25, 2007·The Journal of Nutrition·Connie J RogersStephen D Hursting
Apr 17, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J F van den BergH Tiemeier

❮ Previous
Next ❯

Citations

Mar 26, 2010·The British Journal of Nutrition·Laura Basterfield, John C Mathers
Jul 31, 2010·Physiology & Behavior·Marilyn ArceMark E Wilson
Jan 10, 2012·Journal of Food Science·Jun Ho KimYeonhwa Park
Dec 13, 2018·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·G ManzanaresP G Gandra
Jan 20, 2018·Nature Reviews. Endocrinology·Maximilian KleinertMatthias H Tschöp
Feb 17, 2017·Biology of Sex Differences·Benjamin L SmarrLance J Kriegsfeld
Jun 5, 2021·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Mitsuharu OkutsuKei Nagashima
Aug 24, 2021·Frontiers in Neuroendocrinology·João Paulo Cavalcanti-de-Albuquerque, José Donato

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.