When a motor goes bad: a kinesin regulates neuronal survival

Cell
David R Kaplan, Freda D Miller

Abstract

In this issue of Cell, Midorikawa et al. (2006) demonstrate that the kinesin superfamily member KIF4, a microtubule-based molecular motor, regulates the survival of electrically active neurons in the developing brain by modulating the function of poly(ADP-ribose) polymerase-1 in an unexpected way.

References

Sep 4, 1987·Science·R Levi-Montalcini
Sep 11, 2004·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·W Bradley JacobsFreda D Miller

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Citations

Apr 17, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·T JehleW A Lagrèze
Aug 17, 2010·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Jie GaoChangjun Zhu

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