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When Less is More: "Slicing" Sequencing Data Improves Read Decoding Accuracy and De Novo Assembly Quality

bioRxiv

Jan 3, 2015

Stefano LonardiTimothy J. Close

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Abstract

Since the invention of DNA sequencing in the seventies, computational biologists have had to deal with the problem de novo genome assembly with limited (or insufficient) depth of sequencing. In this work, for the first time we investigate the opposite problem, that is, the challenge of ...read more

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DNA Sequence
Sequence Determinations, DNA
Vigna unguiculata
Barley extract
Clone Cells
Hordeum
Hordeum vulgare
Silo (Dataset)
Barley allergenic extract
Sequencing
20
1
2
Paper Details
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  • When Less is More: "Slicing" Sequencing Data Improves Read Decoding Accuracy and De Novo Assembly Quality

    bioRxiv

    Jan 3, 2015

    Stefano LonardiTimothy J. Close

    PMID: 990013425

    DOI: 10.1101/013425

    Abstract

    Since the invention of DNA sequencing in the seventies, computational biologists have had to deal with the problem de novo genome assembly with limited (or insufficient) depth of sequencing. In this work, for the first time we investigate the opposite problem, that is, the challenge of ...read more

    Mentioned in this Paper

    DNA Sequence
    Sequence Determinations, DNA
    Vigna unguiculata
    Barley extract
    Clone Cells
    20
    1
    2
    Paper Details
    References
    • References
    • Citations

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