'When measurements mean action' decision models for portal image review to eliminate systematic set-up errors

Australasian Radiology
Christopher R WrattenC Hamilton

Abstract

The aim of the present paper is to evaluate how the use of decision models in the review of portal images can eliminate systematic set-up errors during conformal therapy. Sixteen patients undergoing four-field irradiation of prostate cancer have had daily portal images obtained during the first two treatment weeks and weekly thereafter. The magnitude of random and systematic variations has been calculated by comparison of the portal image with the reference simulator images using the two-dimensional decision model embodied in the Hotelling's evaluation process (HEP). Random day-to-day set-up variation was small in this group of patients. Systematic errors were, however, common. In 15 of 16 patients, one or more errors of >2 mm were diagnosed at some stage during treatment. Sixteen of the 23 errors were between 2 and 4 mm. Although there were examples of oversensitivity of the HEP in three cases, and one instance of undersensitivity, the HEP proved highly sensitive to the small (2-4 mm) systematic errors that must be eliminated during high precision radiotherapy. The HEP has proven valuable in diagnosing very small (<4 mm) errors. When combined with the potential for rapid diagnosis of larger (>4 mm) systematic errors using one-...Continue Reading

References

Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·S A RosenthalP H Blitzer
Oct 1, 1985·International Journal of Radiation Oncology, Biology, Physics·I RabinowitzJ Leong
Jul 1, 1994·International Journal of Radiation Oncology, Biology, Physics·R D KortmannM Bamberg
Jul 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·C MitineE van der Schueren
Nov 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M van HerkR E Vijlbrief
Nov 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A BelJ V Lebesque
Nov 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·K G GilhuijsR E Vijlbrief
Aug 1, 1993·International Journal of Radiation Oncology, Biology, Physics·J W DenhamC S Hamilton
Jan 15, 1997·International Journal of Radiation Oncology, Biology, Physics·J HanleyG J Kutcher
Oct 2, 1998·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·L EkbergT Landberg
Sep 16, 1999·International Journal of Radiation Oncology, Biology, Physics·T PereraP Munro
Apr 13, 2000·Australasian Radiology·A SeeJ W Denham
Aug 3, 2001·International Journal of Radiation Oncology, Biology, Physics·H C de Boer, B J Heijmen

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Citations

Mar 18, 2009·The British Journal of Radiology·C M ThompsonJ Vaarkamp
Feb 21, 2008·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Margaret C McEntee

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