When Sick Brain and Hopelessness Meet: Some Aspects of Suicidality in the Neurological Patient.

CNS & Neurological Disorders Drug Targets
A CostanzaMario Amore

Abstract

Neurological diseases expose individuals to a higher risk of suicidal ideation and suicidal behavior, including completed suicides and suicide attempts. They also represent a paradigmatic arena to study the etiopathogenic mechanisms underlying suicidality because they are emblematic of the heterogeneity and complexity of mutual interrelationships characterizing this issue. On the one hand, neurological diseases imply strictly biological impairments that are postulated to be the basis of vulnerability to suicide or result in the need for treatments for which a suicidal risk has been hypothesized. On the other hand, they question some subjective experiences of neurological patients, up to near existential positions. Often, in fact, they are accompanied by severe hopelessness. The latter may originate in, particularly for the most severe neurological diseases, the absence of curative treatments, unpredictable disease progression that leads to acute relapses or chronicity, a decrease in autonomy or selfidentity, progressive social isolation, a sense of becoming useless, and perception of feeling stigmatized. This may ultimately cause a slip into experiencing an absurd condition. At the confluence of neurobiology and hopelessness, f...Continue Reading

References

Dec 1, 1992·Archives of Neurology·E N Stenager, E Stenager
Apr 20, 2001·Journal of Neurology, Neurosurgery, and Psychiatry·S WilsonM Saling
Jul 12, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·David J Burn
Oct 2, 2002·Current Treatment Options in Neurology·David B. Arciniegas, C. Alan Anderson
Apr 3, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Albert F G LeentjensFrans R J Verhey
Apr 14, 2006·Current Opinion in Psychiatry·Hugh Rickards
Jun 27, 2006·Psychological Reports·Maurizio PompiliRoberto Tatarelli
Aug 2, 2008·Brain : a Journal of Neurology·Fang FangWeimin Ye
Oct 23, 2008·Brain : a Journal of Neurology·Valerie VoonElena Moro
Apr 17, 2009·International Psychogeriatrics·Camilla HawKeith Hawton
Oct 21, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christopher J RecklitisLonnie Zeltzer
Sep 10, 2010·Neuroscience and Biobehavioral Reviews·C van HeeringenK Godfrin
Dec 7, 2010·Nature Reviews. Neurology·Maurizio Pompili, Ross J Baldessarini
Jun 15, 2011·Alzheimer Disease and Associated Disorders·Antonella AlbericiAlessandro Padovani
Jun 21, 2011·Journal of the Neurological Sciences·Vladimir S Kostić, Massimo Filippi
Aug 13, 2011·Journal of the Neurological Sciences·Michel Benoit, Philippe H Robert
Nov 15, 2012·Journal of Psychosomatic Research·Maurizio PompiliPaolo Girardi
Feb 23, 2013·International Journal of Legal Medicine·Alessandra CostanzaRomano La Harpe
Jul 3, 2013·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Julia J HsiaoMario F Mendez
Oct 12, 2013·Handbook of Clinical Neurology·Pierre Pollak
Dec 30, 2014·World Journal of Psychiatry·Maurizio PompiliCarla Buttinelli
Jun 1, 2014·The Lancet. Psychiatry·Kees van Heeringen, J John Mann
Dec 10, 2015·JAMA Psychiatry·Dale C HesdorfferW Allen Hauser
May 6, 2016·Frontiers in Psychiatry·Gianluca SerafiniMario Amore
Jul 28, 2016·Current Alzheimer Research·Gianluca SerafiniMaurizio Pompili
Sep 2, 2016·Epilepsy Currents·Alison M Pack
Mar 23, 2018·Journal of Neurology·Astrid EliasenHenrik Horwitz
Oct 20, 2018·International Journal of Clinical Practice·Isabella BerardelliMaurizio Pompili
Nov 16, 2018·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Annie VerschuerenShahram Attarian
Mar 16, 2019·Journal of Affective Disorders·Zachary R KachianJordan Grafman
Jul 5, 2019·CNS & Neurological Disorders Drug Targets·Isabella BerardelliMaurizio Pompili
Apr 1, 2020·International Journal of Environmental Research and Public Health·Alessandra CostanzaAlessandra Canuto

❮ Previous
Next ❯

Citations

Aug 6, 2020·International Journal of Environmental Research and Public Health·Yasutaka OjioChiyo Fujii
Oct 8, 2020·Frontiers in Psychiatry·Alessandra CostanzaMaurizio Pompili
Jan 28, 2021·International Journal of Environmental Research and Public Health·Alessandra CostanzaKhoa D Nguyen
Jul 25, 2021·International Journal of Environmental Research and Public Health·Seulkee HeoMichelle L Bell
Aug 8, 2021·International Journal of Environmental Research and Public Health·Sarah L CorneliusNatalie B Riblet
Sep 2, 2021·Journal of Pain Research·X Michelle AndroulakisDeborah Reyes
Jan 26, 2022·PloS One·Lucie LaflammeMathilde Sengoelge

❮ Previous
Next ❯

Methods Mentioned

BETA
Deep
medical procedure

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Medsurg Nursing : Official Journal of the Academy of Medical-Surgical Nurses
N Farabaugh
Revista médica de Chile
A BarreraF Lolas
JAMA : the Journal of the American Medical Association
A T BeckA Weissman
© 2022 Meta ULC. All rights reserved