When Solving Dyspareunia Is Not Enough to Restore Sexual Function in Women With Deep Infiltrating Endometriosis Treated With Dienogest

Journal of Sex & Marital Therapy
João Paulo Leonardo-PintoDaniela Angerame Yela

Abstract

The aim of the study was to evaluate dyspareunia and sexual function (SF) in women with deep infiltrating endometriosis (DIE) who were treated with dienogest (DNG) for 12 months. The prospective cohort study took place at the University of Campinas, Brazil, and included 30 women with sonographic diagnosis of DIE and sexual dysfunction treated with 2 mg/daily DNG for 12 months. SF parameters were assessed by the Female Sexual Function Index (FSFI) before and after treatment, and dyspareunia was quantified through the visual analog scale (VAS) during the follow-ups performed every three months. Statistical analysis was performed by ANOVA test and through the use of software SAS, Version 9.4. Women were on average 36.13 ± 6.24 years old, and all of them showed sexual dysfunction (FSFI =17.6 ± 5.7) before DNG; 88.3% had dyspareunia as the main symptom related to DIE (VAS before: 5.3 ± 3.1). At the end of the treatment, dyspareunia showed a decrease of intensity (VAS after: 3.7 ± 3.3; p = .0093) and an improvement on FSFI index was accomplished (p = .0023); however, it did not restore SF completely, considering the FSFI cutoff < 26.55. Long-term treatment for DIE with DNG has provided a decrease in dyspareunia and also an enhancemen...Continue Reading

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Feb 24, 2017·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Joao Paulo Leonardo-PintoDaniela Angerame Yela

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Citations

Mar 17, 2020·Current Medical Research and Opinion·Ally MurjiMaria Yarmolinskaya
Sep 4, 2020·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Faustino R Pérez-LópezPeter Chedraui
Sep 29, 2021·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Pınar Yalçın BahatEda Üreyen Özdemir
Apr 28, 2021·Minerva Obstetrics and Gynecology·Valentina RossiFilippo M Nimbi

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