When to vaccinate a fluctuating wildlife population: Is timing everything?

The Journal of Applied Ecology
Courtney L SchreinerAndrew J Basinski

Abstract

Wildlife vaccination is an important tool for managing the burden of infectious disease in human populations, domesticated livestock and various iconic wildlife. Although substantial progress has been made in the field of vaccine designs for wildlife, there is a gap in our understanding of how to time wildlife vaccination, relative to host demography, to best protect a population.We use a mathematical model and computer simulations to assess the outcomes of vaccination campaigns that deploy vaccines once per annual population cycle.Optimal timing of vaccination is an important consideration in animals with short to intermediate life spans and a short birthing season. Vaccines that are deployed shortly after the birthing season best protect the host population.The importance of timing is greater in wildlife pathogens that have a high rate of transmission and a short recovery period. Vaccinating at the end of the birthing season best reduces the mean abundance of pathogen-infected hosts. Delaying vaccination until later in the year can facilitate pathogen elimination. Policy Implications. Tuning wildlife vaccination campaigns to host demography and pathogen traits can substantially increase the effectiveness of a campaign. Our re...Continue Reading

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Citations

Jul 29, 2020·Nature Ecology & Evolution·Scott L Nuismer, James J Bull
Mar 9, 2021·Virus Evolution·Nathan C LaymanScott L Nuismer
Mar 12, 2021·Parasite Immunology·Jolieke G van Oosterwijk

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