When Trust Is Not Enough: A Serial Mediation Model Explaining the Effect of Race Identity, eHealth Information Efficacy, and Information Behavior on Intention to Participate in Clinical Research

Health Education & Behavior : the Official Publication of the Society for Public Health Education
Yulia A Strekalova

Abstract

Black participants remain significantly underrepresented in clinical research. Mistrust in medical researchers has been named a key barrier to the successful enrollment of minority study participants. However, trust is a social-interactional construct, and its effects on behavior are complex. This study hypothesized that intention to participate in clinical research is mediated by trust in medical researchers, eHealth literacy, and information seeking behavior. The data were collected through an online survey ( N = 340) and analyzed to identify serial mediation. The model showed insignificant direct effect of race identity on behavioral intention, c' = -0.19, t(335) = -1.22, p = .22, but a significant total effect, c = -0.44, t(335) = -2.59, p < .01. The indirect effect of race identity on behavioral intention was also significant. The positive effect of trust in medical researchers on decisions to participate in clinical research can be amplified by stronger eHealth literacy and active information seeking, which can be supported through focused strategic health education and communication interventions. A focus on the development of information literacy that could provide prospective minority research volunteers with skills fo...Continue Reading

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Citations

Oct 30, 2019·Journal of Clinical and Translational Science·Yiyang LiuLinda B Cottler
Mar 6, 2021·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Jessica Gall Myrick, Michael Hendryx
May 4, 2021·The Journal of Head Trauma Rehabilitation·Jessica WallaceJohna K Register-Mihalik
Dec 7, 2020·The Annals of Thoracic Surgery·Stephen J Huddleston, Rosemary F Kelly

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