When Ventricular Cerebrospinal Fluid Assessment Misleads: Basal Meningitis and the Importance of Lumbar Puncture Sampling

Open Forum Infectious Diseases
Sadid F KhanAlan C Street

Abstract

The diagnosis of central nervous system (CNS) infection relies upon analysis of cerebrospinal fluid (CSF). We present 4 cases of CNS infections associated with basal meningitis and hydrocephalus with normal ventricular CSF but grossly abnormal lumbar CSF. We discuss CSF ventricular-lumbar composition gradients and putative pathophysiological mechanisms and highlight clinical clues for clinicians.

References

Nov 30, 2004·Critical Care : the Official Journal of the Critical Care Forum·Walid NaijaAlexandre Mebazaa
May 21, 2011·Neurocirugía·S Alfayate-MiguélezJ F Martínez-Lage
Dec 12, 2013·The American Journal of the Medical Sciences·Eric Chow, Stephanie B Troy

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BETA
PCR

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