When will selective lymphadenectomy become standard of care in melanoma?

International Journal of Clinical Practice
R Russell-Jones

Abstract

In 2006 Meiron Thomas, writing in the British Journal of Surgery, made the following statement about the value of sentinel lymph node biopsy (SLNB) as a staging procedure in cutaneous malignant melanoma (1): "Perhaps a more important concern for those hoping to gain reassurance from accurate nodal staging relates to positive SN(S) that are prognostically inaccurate, information that can be devastating for the patient, leading to unnecessary lymphadenectomy and possibly unnecessary adjuvant therapy". In September 2011 Meyrick Ross and Gershenwald, writing in the Journal of Surgical Oncology, made the following statement about the management of patients with cutaneous malignant melanoma (2): "Sentinel node biopsy has become an important component of the initial management of many of these patients for accurate staging of regional lymph nodes, as well as enhanced regional disease control and improved survival in the patients with microscopically involved nodes." These two extremes have polarized the debate about the proper management of patients with malignant melanoma and have lead to widespread confusion and dismay amongst practicing clinicians, GP's and patient groups. In fact both statements are inaccurate, misleading and resu...Continue Reading

References

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Dec 19, 2002·American Journal of Surgery·Celia ChaoUNKNOWN Sunbelt Melanoma Trial Group
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Dec 16, 2003·American Journal of Surgery·Timothy R FincherJoseph A Kuhn
Nov 27, 2004·BMJ : British Medical Journal·Robin Russell-JonesEduardo Calonje
Sep 15, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gary H LymanUNKNOWN American Society of Clinical Oncology
Nov 26, 2005·The British Journal of Dermatology·R Russell-Jones
Jan 4, 2006·The Lancet Oncology·J Meirion Thomas
Jan 25, 2006·The British Journal of Surgery·J M Thomas
Aug 17, 2006·The British Journal of Dermatology·A J Hayes, J M Thomas
Sep 29, 2006·The New England Journal of Medicine·Donald L MortonUNKNOWN MSLT Group
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Jun 7, 2011·The New England Journal of Medicine·Paul B ChapmanUNKNOWN BRIM-3 Study Group
Aug 23, 2011·Journal of Surgical Oncology·Merrick I Ross, Jeffrey E Gershenwald

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Citations

May 16, 2014·Annals of Surgical Innovation and Research·George L Balalis, Sarah K Thompson
Jun 9, 2016·The British Journal of Dermatology·R Russell-Jones

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