PMID: 6107963Jun 1, 1980Paper

Where is the spawning reflex receptor for neurohypophysial peptides in the killifish, Fundulus heteroclitus?

Revue Canadienne De Biologie
G E PICKFORDJ N Knight

Abstract

Arginine vasotocin, injected into the third vehicle of 10 brain-cannulated, unanesthetized male Fundulus heteroclitus at estimated doses of 0.4 and 40 mU/g wt., failed to elicit a spawning reflex in five recipients; each had been both pre- and post-tested for responsiveness to intraperitoneal injections. Five others responded at the 40 mU/g dose and one also at the 0.4 mU/g dose: the first response occurred after a long delay, similar to that after intraperitoneal injection. Escape into the peripheral circulation is implicated. Since the N. preopticus is known to participate in the spawning reflex response, an indirect pathway from the peripheral AVT-receptor to the hypothalamic nucleus is suspected. Substances that might have behavioral effects, or function as neuro-transmitters, were tested with negative results: ACTH, epinephrine, norepinephrine, GABA, dopamine, L-dopa, cAMP, cGMP and the prostaglandins PGA2, PGE2 and PGE2 alpha. Serotonin failed to elicit a spawning reflex but caused rapidly developing symptoms of hypoxia. An immediate single spawning reflex was observed on three occasions after intracerebral injection: once after each of the otherwise ineffective hypothalamic releasing hormones, LRF and TRF, and once after...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.