Where tendons and ligaments meet bone: attachment sites ('entheses') in relation to exercise and/or mechanical load.

Journal of Anatomy
M BenjaminS Milz

Abstract

Entheses (insertion sites, osteotendinous junctions, osteoligamentous junctions) are sites of stress concentration at the region where tendons and ligaments attach to bone. Consequently, they are commonly subject to overuse injuries (enthesopathies) that are well documented in a number of sports. In this review, we focus on the structure-function correlations of entheses on both the hard and the soft tissue sides of the junction. Particular attention is paid to mechanical factors that influence form and function and thus to exploring the relationship between entheses and exercise. The molecular parameters indicative of adaptation to mechanical stress are evaluated, and the basis on which entheses are classified is explained. The application of the 'enthesis organ' concept (a collection of tissues adjacent to the enthesis itself, which jointly serve the common function of stress dissipation) to understanding enthesopathies is considered and novel roles of adipose tissue at entheses are reviewed. A distinction is made between different locations of fat at entheses, and possible functions include space-filling and proprioception. The basic anchorage role of entheses is considered in detail and comparisons are explored between enth...Continue Reading

References

Nov 1, 1976·Archivum Histologicum Japonicum = Nihon Soshikigaku Kiroku·M Yamada
Nov 1, 1977·The American Journal of Sports Medicine·J G Garrick
Jun 1, 1991·Radiology·C J BerginA Macovski
Jan 1, 1989·International Review of Cytology·K G Vogel, T J Koob
Nov 1, 1988·Annals of the Rheumatic Diseases·J J CanosoV M Runge
May 1, 1974·Atherosclerosis·C W AdamsC J Hunter-Craig
May 1, 1995·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·M P BostromV M Rosen
Jul 1, 1995·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·A RufaiM Benjamin
Nov 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R M HenkelmanM J Bronskill
Feb 1, 1997·Annals of the Rheumatic Diseases·J RogersP Dieppe
Jun 15, 1997·Archives of Biochemistry and Biophysics·J R RobbinsK G Vogel
Aug 25, 1997·Experimental Cell Research·H YamashitaK Miyazono
Apr 8, 1998·Acta Radiologica·T MovinP Aspelin
Apr 29, 1998·Matrix Biology : Journal of the International Society for Matrix Biology·A D WaggettM Benjamin
Jun 26, 1998·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·J L CookJ D Wark
Oct 23, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S W VolkP S Leboy
Feb 24, 1999·Journal of Anatomy·M Benjamin, J R Ralphs
Mar 12, 1999·Mechanisms of Development·I S KimS Mundlos
Nov 30, 1999·AJR. American Journal of Roentgenology·M A BredellaH K Genant
Dec 28, 1999·Molecular and Cellular Endocrinology·R C Olney, E B Mougey
Feb 9, 2000·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·U M KujalaE Karaharju
Mar 23, 2000·Arthritis and Rheumatism·M BenjaminJ R Ralphs
Apr 6, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·M Garcia-RamirezL Audi
Aug 5, 2000·Baillière's Best Practice & Research. Clinical Rheumatology·B Mazières, J Rovensky
Sep 12, 2000·Matrix Biology : Journal of the International Society for Matrix Biology·B de CrombruggheW Huang
Sep 20, 2000·Anatomy and Embryology·T Hems, B Tillmann
Nov 15, 2000·Journal of Biomedical Materials Research·G W MarshallS J Marshall
Nov 23, 2000·Annals of the Rheumatic Diseases·J BraunJ Sieper
Feb 13, 2001·Mechanisms of Development·C I Colnot, J A Helms
Feb 24, 2001·Proceedings. Biological Sciences·T FukunagaC N Maganaris
Apr 3, 2001·Trends in Cardiovascular Medicine·H P Gerber, N Ferrara

❮ Previous
Next ❯

Citations

Feb 26, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Mahmut Nedim DoralNicola Maffulli
Apr 3, 2012·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Vedran LovricWilliam R Walsh
Dec 12, 2012·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Carl M AsklingThomas M Best
Jul 18, 2009·Calcified Tissue International·Guoying LiangCarolyn M Macica
May 16, 2009·Urological Research·Christoph Schmitz, Rocco DePace
Dec 4, 2010·International Orthopaedics·Jian ZhaoXiao Hua Pan
Nov 26, 2010·International Orthopaedics·Jian ChenWen Yuan
Sep 15, 2012·International Orthopaedics·Sagar Narang
Jan 22, 2013·Rheumatology International·Abdurrahman TufanBerna Goker
Feb 14, 2009·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Koji HayashiYoshinori Takakura
May 18, 2013·Bulletin of Mathematical Biology·Mark S Thompson
Nov 30, 2012·Annals of Nuclear Medicine·Yoshinori TaniguchiYoshio Terada
Aug 21, 2013·Differentiation; Research in Biological Diversity·Yulia ShwartzElazar Zelzer
Jul 3, 2010·Tissue Engineering. Part a·Jennifer Z PaxtonKeith Baar
May 24, 2012·Current Opinion in Rheumatology·Maria Antonietta D'Agostino
Mar 29, 2008·Science·Ali MiserezJ Herbert Waite
Jan 5, 2012·Arthritis·Alfonse T MasiJacqueline Henderson
Jul 1, 2009·Sports Health·Christopher Kaeding, Thomas M Best
Jan 10, 2013·JRSM Short Reports·Qmk Bismil, Msk Bismil
Feb 24, 2009·AJR. American Journal of Roentgenology·Mani WangwinyuviratDonald Resnick
Oct 22, 2009·AJR. American Journal of Roentgenology·Florian M BuckJürg Hodler
Aug 24, 2010·AJR. American Journal of Roentgenology·Janis M MillerJohn O L Delancey
Aug 24, 2012·AJR. American Journal of Roentgenology·Jeffrey W Prescott, Joseph S Yu
Mar 10, 2010·Regenerative Medicine·Bibhukalyan Prasad NayakGyan Ranjan Satpathy
Mar 28, 2012·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·B Van RyssenH van Bree
May 15, 2012·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·E de BakkerB Van Ryssen
Jun 27, 2013·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·E de BakkerB Van Ryssen
Jan 1, 2010·International Journal of Therapeutic Massage & Bodywork·Alfonse T MasiYousef Ghandour
Jul 23, 2009·International Journal of Biological Sciences·Sirkka Liisa HostikkaEllen M Carpenter
Mar 7, 2014·Indian Journal of Orthopaedics·Zhiqi ZhuPeng Li
Jan 29, 2014·Forensic Science International : Synergy·Nicolene LotteringLaura S Gregory
Oct 17, 2013·Biotechnology Letters·Alistair BannermanLiam M Grover
Jun 29, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Robert ŚmigielskiRainer Siebold
Jan 30, 2014·Skeletal Radiology·Mohammad SamimHicham Moukaddam
Dec 24, 2013·Reumatología clinica·M Cristina Mata Arnaiz, Eugenio de Miguel Mendieta

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Scandinavian Journal of Medicine & Science in Sports
H M Shaw, M Benjamin
Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
M BenjaminJ R Ralphs
Scandinavian Journal of Medicine & Science in Sports
M Benjamin, Dennis McGonagle
© 2022 Meta ULC. All rights reserved