Which dose constraints on which critical organs in paediatric radiation therapy?

Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
L Claude, A Laprie

Abstract

Cancers in childhood are rare, representing 1% of all the cancers in developing countries. On the whole, the overall survival approaches 75% at 5 years. The radiation dose decrease in lots of indications as well as better optimized planning treatments lead to decrease the long-term toxicities in some indications. However, the radiation toxicity remains frequent, often specific of pediatric situations. Long-term toxicities are mainly neurologic, sensitive, endocrine, or linked to growth impairment (bones or muscular). Radio-induced second-cancers are also frequent after a long follow-up after cancer in childhood but will not be discussed here. Doses to critical organs as well as the most frequent radio-induced late-effects will be discussed in this paper.

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Citations

Jul 17, 2016·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·C Demoor-GoldschmidtV Bernier
Apr 6, 2017·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·C Demoor-GoldschmidtS Supiot
Dec 19, 2016·Bulletin du cancer·Brice FresneauCharlotte Demoor-Goldschmidt
Jul 20, 2019·The British Journal of Radiology·Line ClaudeDaniel Orbach
Sep 14, 2018·Radiation Oncology·Sophie C HuijskensArjan Bel
Aug 11, 2020·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·E JouglarS Supiot
Sep 25, 2020·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Michele MaddaloNunziata D'Abbiero

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