Which factors affect the choice of the inhaler in chronic obstructive respiratory diseases?

Pulmonary Pharmacology & Therapeutics
Nicola ScichiloneAlessandro Sanduzzi

Abstract

Inhalation is the preferred route of drug administration in chronic respiratory diseases because it optimises delivery of the active compounds to the targeted site and minimises side effects from systemic distribution. The choice of a device should be made after careful evaluation of the patient's clinical condition (degree of airway obstruction, comorbidities), as well as their ability to coordinate the inhalation manoeuvre and to generate sufficient inspiratory flow. These patient factors must be aligned with the specific advantages and limitations of each inhaler when making this important choice. Finally, adherence to treatment is not the responsibility of the patient alone, but should be shared also by clinicians. Clinicians have access to a wide selection of pressurised metered dose inhalers (pMDIs) and dry powder inhalers (DPIs) that can be used effectively when matched to the needs of individual patients; this should be perceived as an opportunity rather than a limitation.

References

May 1, 1996·American Journal of Respiratory and Critical Care Medicine·L BorgströmR Pauwels
Aug 6, 1995·Journal of Aerosol Medicine : the Official Journal of the International Society for Aerosols in Medicine·B Olsson
Aug 28, 1999·Respiratory Medicine·M H DewarG K Crompton
Dec 22, 1999·The European Respiratory Journal·J van der PalenE R Seydel
Dec 12, 2001·British Journal of Clinical Pharmacology·L ThorssonC G Löfdahl
Feb 28, 2002·The European Respiratory Journal·V Giraud, N Roche
Aug 2, 2003·American Journal of Respiratory and Critical Care Medicine·Lone Agertoft, Soren Pedersen
Aug 5, 2003·Journal of Applied Physiology·Omar S UsmaniPeter J Barnes
Dec 8, 2004·Immunology and Allergy Clinics of North America·Bruce G Bender, Sarah E Bender
Nov 4, 2005·The New England Journal of Medicine·Ronald J Campbell
Dec 15, 2005·International Journal of Clinical Practice·L BorgströmL Thorsson
Mar 8, 2006·Current Opinion in Allergy and Clinical Immunology·Montserrat M GravesJay M Portnoy
Apr 6, 2006·International Journal of Pharmaceutics·Walid Y TarsinHenry Chrystyn
Jan 6, 2009·BMC Pulmonary Medicine·Mike ThomasJulie von Ziegenweidt
Sep 17, 2010·Current Medical Research and Opinion·Richard PavkovIlse Rietveld
Feb 12, 2011·The European Respiratory Journal·B L LaubeUNKNOWN International Society for Aerosols in Medicine
Sep 29, 2011·Respiratory Care·Bruce K Rubin
Mar 1, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Chet L LeachJacob D McDonald
Aug 27, 2013·Expert Review of Clinical Pharmacology·Mathieu Molimard, Peter D'Andrea

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Citations

Aug 23, 2016·Expert Review of Respiratory Medicine·Philippe Rogueda, Daniela Traini
Aug 24, 2016·Expert Review of Respiratory Medicine·Dejan RadovanovicPierachille Santus
Dec 7, 2017·Postgraduate Medicine·Michael DePietroMichael Riebe
Jan 18, 2018·Respiratory Research·Omar Sharif UsmaniRichard Dekhuijzen
Dec 14, 2019·COPD·Chitra Lal, Akram Khan
Mar 11, 2020·Journal of Clinical Medicine·Marios PanagiotouNikoletta Rovina
Apr 3, 2020·Expert Opinion on Pharmacotherapy·Sabina Antonela AntoniuMihaela Grigore
Oct 1, 2017·Italian Journal of Pediatrics·Daniela PosaSusanne Lau
Jul 21, 2020·Expert Opinion on Pharmacotherapy·Timothy E AlbertsonSusan Murin
Jul 2, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Alberto BraghiroliNicola Scichilone
May 10, 2017·Multidisciplinary Respiratory Medicine·Dejan RadovanovicMarco Mantero
Oct 3, 2020·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·V RajeshMelcy Cleetus
Jul 19, 2018·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Jens Markus BorghardtAshish Sharma

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