Which patients benefit specifically from short-term psychodynamic psychotherapy (STPP) for depression? Study protocol of a systematic review and meta-analysis of individual participant data

BMJ Open
Ellen DriessenPim Cuijpers

Abstract

Short-term psychodynamic psychotherapy (STPP) is an empirically supported treatment that is often used to treat depression. However, it is largely unclear if certain subgroups of depressed patients can benefit specifically from this treatment method. We describe the protocol for a systematic review and meta-analysis of individual participant data (IPD) aimed at identifying predictors and moderators of STPP for depression efficacy. We will conduct a systematic literature search in multiple bibliographic databases (PubMed, PsycINFO, Embase.com, Web of Science and Cochrane's Central Register of Controlled Trials), 'grey literature' databases (GLIN and UMI ProQuest) and a prospective trial register (http://www.controlled-trials.com). We will include studies reporting (a) outcomes on standardised measures of (b) depressed (c) adult patients (d) receiving STPP. We will next invite the authors of these studies to share the participant-level data of their trials and combine these data to conduct IPD meta-analyses. The primary outcome for this study is post-treatment efficacy as assessed by a continuous depression measure. Potential predictors and moderators include all sociodemographic variables, clinical variables and psychological pa...Continue Reading

References

Jul 27, 2001·Statistics in Medicine·J P HigginsS G Thompson
Oct 9, 2002·Archives of General Psychiatry·Helena Chmura KraemerW Stewart Agras
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Sep 19, 2006·Journal of Clinical Epidemiology·A Rogier T DondersKarel G M Moons
Dec 12, 2007·Statistics in Medicine·Richard D RileyFlorent Boutitie
Apr 26, 2008·BMJ : British Medical Journal·Gordon H GuyattUNKNOWN GRADE Working Group
May 20, 2008·BMC Psychiatry·Pim CuijpersGerhard Andersson
Feb 12, 2009·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Jacques P Barber
Apr 22, 2009·Journal of the Royal Statistical Society. Series A, (Statistics in Society)·Julian P T HigginsDavid J Spiegelhalter
Jul 1, 2009·BMJ : British Medical Journal·Jonathan A C SterneJames R Carpenter
Sep 22, 2009·Clinical Psychology Review·Ellen DriessenJack J M Dekker
Feb 9, 2010·BMJ : British Medical Journal·Richard D RileyGhada Abo-Zaid
Sep 30, 2010·Journal of Consulting and Clinical Psychology·Ellen DriessenJack J M Dekker
Dec 8, 2010·Archives of General Psychiatry·Steven C Marcus, Mark Olfson
Jul 26, 2011·BMJ : British Medical Journal·Jonathan A C SterneJulian P T Higgins
Mar 1, 2012·The Psychiatric Clinics of North America·Ronald C Kessler
Apr 15, 2014·Annals of Internal Medicine·John E CornellSteven N Goodman
Jun 21, 2015·Contemporary Clinical Trials·Mark SimmondsLesley Stewart
Aug 19, 2015·Clinical Psychology Review·Ellen DriessenPim Cuijpers
Aug 20, 2015·Research Synthesis Methods·Thomas P A DebrayUNKNOWN GetReal Methods Review Group
Mar 5, 2017·BMJ : British Medical Journal·David J FisherJayne F Tierney

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Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

glmertree
ProQuest
R
Stata

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