Which way to manipulate host reproduction? Wolbachia that cause cytoplasmic incompatibility are easily invaded by sex ratio-distorting mutants

The American Naturalist
G D D HurstAndrew Pomiankowski

Abstract

The bacterium Wolbachia manipulates its hosts by inducing cytoplasmic incompatibility (CI), where zygotes formed from crosses between uninfected mothers and infected fathers die. In addition, it distorts the host's sex ratio via male killing, parthenogenesis induction, or feminization. Here, we model transitions between these states, examining the evolution of mutants of CI strains that retain both the ability to induce and resist CI but, in addition, cause sex ratio distortion. The model shows that CI strains are highly susceptible to invasion and subsequent elimination by these mutants. For all three types of sex ratio distortion, there is some parameter space in which the strain showing sex ratio distortion becomes extinct following exclusion of the progenitor CI strain, leaving the population uninfected. Extinction of the new Wolbachia strain is common for the case of male killing but rarer for parthenogenesis induction and feminization. Our models predict that CI strains of Wolbachia will occur most commonly in hosts that are male heterogametic, where there is little interaction between siblings because these hosts are unlikely to favor the spread of male killing, feminization, or parthenogenesis induction. The models rais...Continue Reading

References

Nov 23, 1992·Proceedings. Biological Sciences·F RoussetM Solignac
Jan 21, 1991·Journal of Theoretical Biology·L D Hurst
Jul 22, 1995·Proceedings. Biological Sciences·J H WerrenL R Guo
Sep 1, 1999·Insect Molecular Biology·M M Van MeerR Stouthamer
Nov 5, 1999·Annual Review of Microbiology·R StouthamerG D Hurst
Sep 6, 2000·Proceedings. Biological Sciences·J H Werren, D M Windsor
Sep 13, 2000·Proceedings. Biological Sciences·R F Fialho, L Stevens
Feb 1, 1991·Trends in Ecology & Evolution·F Rousset, M Raymond

❮ Previous
Next ❯

Citations

Aug 30, 2008·Proceedings. Biological Sciences·Vincent A A JansenH Charles J Godfray
Jan 12, 2011·Die Naturwissenschaften·Ken KraaijeveldJacques J M van Alphen
Aug 29, 2009·Medical and Veterinary Entomology·S PampiglioneM Trentini
Feb 27, 2008·Evolution; International Journal of Organic Evolution·Emily A HornettSylvain Charlat
Feb 20, 2007·Journal of Evolutionary Biology·J EngelstädterG D D Hurst
Dec 31, 2009·Journal of Evolutionary Biology·E A HornettG D D Hurst
Oct 20, 2004·Experimental Parasitology·Andrea LuchettiMassimo Trentini
Oct 27, 2004·Journal of Theoretical Biology·Jan EngelstädterPeter Hammerstein
Jun 11, 2016·Evolution; International Journal of Organic Evolution·Kelly M RichardsonAry A Hoffmann
Jul 30, 2002·Molecular Ecology·Francis M JigginsGregory D D Hurst
Aug 13, 2004·Proceedings. Biological Sciences·Masato HirokiYoshiomi Kato
Mar 1, 2005·Proceedings. Biological Sciences·Eleanor R Haine, James M Cook
Aug 30, 2002·Molecular Biology and Evolution·Francis M Jiggins
Dec 14, 2017·Heredity·Roman Zug, Peter Hammerstein
Dec 26, 2018·Journal of Tropical Medicine·El Hadji Amadou NiangOleg Mediannikov

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Evolution; International Journal of Organic Evolution
John Jaenike
Proceedings. Biological Sciences
R F Fialho, L Stevens
Annual Review of Entomology
John H Werren
BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology
Denis PoinsotHervé Merçot
© 2022 Meta ULC. All rights reserved