Abstract
Recent studies have demonstrated that brief daily IAE (intermittent altitude exposure) was equally as effective as continuous altitude residence in inducing physiological adaptations consistent with altitude acclimatization. Although the positive benefits of IAE have been clearly defined, the potential negative consequences of IAE on health, specifically the immune system, remain undefined. The present study determined the effects of IAE on WBC (white blood cell) and hormonal responses during rest and exercise at 4300 m altitude. Six lowlanders (age, 23+/-2 years; body weight, 77+/-6 kg; values are means+/-S.E.M.) completed a VO(2)max (maximal O(2) uptake) and submaximal cycle ergometer test during a 30-h SL (sea level) exposure and during a 30 h exposure to 4300 m altitude-equivalent once before (PreIAE) and once after (PostIAE) a 3-week period of IAE (4 hxday(-1), 5 daysxweek(-1), 4300 m). The submaximal cycle ergometer test consisted of two consecutive 15-min work bouts at 40% and 70% of altitude-specific VO(2)max. Blood samples were obtained at rest and during both exercise work bouts for measurements of WBC count, leucocyte subset counts, cortisol, adrenaline (epinephrine) and noradrenaline (norepinephrine). WBC, neutrophi...Continue Reading
References
Aug 1, 1974·Journal of Applied Physiology·D B Dill, D L Costill
May 1, 1969·Journal of Applied Physiology·J P HannonC W Harris
Jan 1, 1982·Immunological Reviews·T R Cupps, A S Fauci
Feb 1, 1995·Journal of Applied Physiology·M KlokkerB K Pedersen
Jan 1, 1994·European Journal of Applied Physiology and Occupational Physiology·G SavoureyJ Bittel
Jan 1, 1994·European Journal of Applied Physiology and Occupational Physiology·K EngfredB D Levine
Mar 1, 1993·Journal of Applied Physiology·M KlokkerB K Pedersen
Jun 1, 1996·Brain, Behavior, and Immunity·R J BenschopM Schedlowski
Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·G SavoureyJ Bittel
Feb 12, 1998·European Journal of Applied Physiology and Occupational Physiology·G SavoureyJ Bittel
Mar 26, 1998·Brain, Behavior, and Immunity·F S Dhabhar, B S McEwen
May 8, 1999·Journal of Applied Physiology·B A BeidlemanA Cymerman
Jan 21, 2000·Journal of Applied Physiology·B BraunG E Butterfield
Mar 7, 2002·Medicine and Science in Sports and Exercise·Beth A BeidlemanAllen Cymerman
Feb 4, 2003·Exercise and Sport Sciences Reviews·Robert S Mazzeo, John T Reeves
Jun 24, 2003·Journal of Applied Physiology·Beth A BeidlemanMichael N Sawka
Aug 28, 2003·Clinical and Experimental Pharmacology & Physiology·Y HitomiH Ohno
Oct 17, 2003·Clinical Science·Beth A BeidlemanMichael N Sawka
Aug 31, 2004·Journal of Applied Physiology·Alexander ChoukèrManfred Thiel
May 12, 2005·Scandinavian Journal of Medicine & Science in Sports·C LundbyR Damsgaard
Citations
May 23, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Jie ChaoNorberto C Gonzalez
Feb 27, 2009·American Journal of Respiratory Cell and Molecular Biology·Jie ChaoNorberto C Gonzalez
Jun 24, 2009·Respiratory Research·Jie ChaoNorberto C Gonzalez
Dec 18, 2007·High Altitude Medicine & Biology·Patricia SiquésRafael Herruzo
Mar 16, 2011·Respiratory Physiology & Neurobiology·Jie ChaoNorberto C Gonzalez
Nov 20, 2013·Health Care for Women International·Samaya VanTyler, Laurene Sheilds
Apr 10, 2020·American Journal of Rhinology & Allergy·Giancarlo OttavianoAndrea Ermolao
Feb 15, 2020·European Journal of Applied Physiology·Barbara TobinGillian M C Renshaw
Mar 20, 2020·International Journal of Environmental Research and Public Health·Won-Sang JungHun-Young Park
Apr 13, 2010·Immunological Investigations·K P Mishra, Lilly Ganju