White dot fovea

American Journal of Ophthalmology
K YokotsukaK Shimizu

Abstract

To describe a newly identified clinical entity tentatively named white dot fovea. We examined by scanning laser ophthalmoscopy 58 eyes of 30 patients (mean age, 64 years) who had white dots in the fovea (anatomically defined as the foveola) simulating macular hole. In addition, the retinal surfaces of 30 autopsy eyes from donors aged 70 years or older were observed by scanning electron microscopy. White dot fovea was bilateral in 28 of 30 patients (93%). It was characterized by the presence of numerous white dots on the foveal surface distributed either diffusely or along the foveal margin, forming a gray ring. There was no subjective symptom or visual disturbance. The condition was best seen by a scanning laser ophthalmoscope using argon blue laser as the light source. The white dots numbered from 100 to 300 per eye. Each dot was approximately 5 microns in diameter. Scanning electron microscopy showed foveal granules simulating the white dots in five of 30 autopsy eyes (17%). The granules had multiple protrusions with cilia-like structures resembling glial cells. This glia-like structure seemed to be a counterpart of clinically observed white dot fovea. White dot fovea is a new, frequent, and apparently innocuous clinical enti...Continue Reading

References

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Jan 1, 1986·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·S KishiS Yamazaki
Aug 1, 1969·Archives of Ophthalmology·E Yamada
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Oct 1, 1995·American Journal of Ophthalmology·S KishiK Shimizu
Apr 1, 1964·Archives of Ophthalmology·D G COGAN, D D FEDERMAN

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Citations

Jun 11, 2014·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Kadriye Erkan TuranMichael C Brodsky
Apr 4, 2019·Ophthalmic Genetics·Vittoria MurroStanislao Rizzo
Dec 4, 2019·Glia·Andreas Reichenbach, Andreas Bringmann
Jan 5, 2002·Retina·H R McDonald
Mar 29, 2021·American Journal of Ophthalmology·Christelle GrondinDavid Sarraf
Dec 11, 2020·Experimental Eye Research·Andreas BringmannPeter Wiedemann
Jun 9, 2021·Progress in Retinal and Eye Research·Andreas BringmannPeter Wiedemann

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