White-light-exciting, layer-by-layer-assembled ZnCdHgSe quantum dots/polymerized ionic liquid hybrid film for highly sensitive photoelectrochemical immunosensing of neuron specific enolase

Analytical Chemistry
Xiangyang YuChunya Li

Abstract

ZnCdHgSe quantum dots (QDs) functionalized with N-acetyl-l-cysteine were synthesized and characterized. Through layer-by-layer assembling, the ZnCdHgSe QDs was integrated with a polymerized 1-decyl-3-[3-pyrrole-1-yl-propyl]imidazolium tetrafluoroborate (PDPIT) ionic liquid film modified indium tin oxide (ITO) electrode to fabricated a photoelectrochemical interface for the immobilization of rabbit antihuman neuron specific enolase (anti-NSE). After being treated with glutaraldehyde vapor and bovine serum albumin successively, an anti-NSE/ZnCdHgSe QDs/PDPIT/ITO sensing platform was established. Simplely using a white-light LED as an excitation source, the immunoassay of neuron specific enolase (NSE) was achieved through monitoring the photocurrent variation. The polymerized ionic liquid film was demonstrated to be an important element to enhance the photocurrent response of ZnCdHgSe QDs. The anti-NSE/ZnCdHgSe QDs/PDPIT/ITO based immunosensor presents excellent performances in neuron specific enolase determination. The photocurrent variation before and after being interacted with NSE exhibits a good linear relationship with the logarithm of its concentration (log cNSE) in the range from 1.0 pg mL(-1) to 100 ng mL(-1). The limit o...Continue Reading

References

Jan 1, 1987·Annual Review of Neuroscience·P J Marangos, D E Schmechel
Apr 3, 2001·Nature Biotechnology·R Weissleder
Sep 12, 2001·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·M CioffiA M Molinari
Mar 2, 2002·Science·Hiroaki Kitano
Mar 21, 2002·The Lancet Oncology·P R SrinivasS Srivastava
Feb 9, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Yang LiuJinghong Li
Jun 2, 2005·Nature Materials·Igor L MedintzHedi Mattoussi
Jul 27, 2006·Journal of the American Chemical Society·Naoufel HaddourSerge Cosnier
May 5, 2007·Analytical Chemistry·Jeffrey C SmithDaniel Figeys
May 24, 2007·Chemical Reviews·Vasile I Pârvulescu, Christopher Hardacre
Jun 15, 2007·Chemical Reviews·Fred van Rantwijk, Roger A Sheldon
Nov 21, 2007·Accounts of Chemical Research·Robin D Rogers, Gregory A Voth
Sep 15, 2009·Biosensors & Bioelectronics·Guang-Li WangShou-Zhong Fu
Mar 30, 2010·Analytical and Bioanalytical Chemistry·Ravindran Girija AswathyD Sakthi Kumar
Jul 6, 2010·Chemical Society Reviews·Tina ErdmengerUlrich S Schubert
Jan 1, 2009·Cancer Biomarkers : Section a of Disease Markers·Rafael MolinaPetra Stieber
Oct 12, 2010·Biosensors & Bioelectronics·Muhammad J A Shiddiky, Angel A J Torriero
Aug 23, 2011·Chemical Society Reviews·Xiao-Bing Lu, Donald J Darensbourg
Aug 30, 2011·Analytical Chemistry·J TanneF Lisdat
Nov 21, 2012·Chemical Society Reviews·Tamar L Greaves, Calum J Drummond
Aug 28, 2013·Chemical Society Reviews·Siti Nurhanna Riduan, Yugen Zhang
Jan 16, 2014·The Journal of Physical Chemistry Letters·Tsukasa TorimotoSusumu Kuwabata

❮ Previous
Next ❯

Citations

Jan 27, 2017·Chemical Reviews·Ksenia S EgorovaValentine P Ananikov
Jul 29, 2017·Chemical Reviews·Zdeněk FarkaPetr Skládal
Mar 7, 2019·Physical Chemistry Chemical Physics : PCCP·Anja SchlosserNadja C Bigall
Nov 14, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Lan GeWang Kun
Jan 21, 2017·Analytical Chemistry·Wei WenYuehe Lin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.