White matter lesions and vascular cognitive impairment: part 1: typical and unusual causes.

Clinical Neuroradiology
M NichtweissE Hattingen

Abstract

While the diagnosis of vascular dementia rests on established radiomorphological criteria, the term vascular cognitive impairment hitherto is less clear cut and hence the interpretation of white matter changes (WMC) widely held to be caused by vascular disease is pivotal. Part one of this review deals with the description of WMC and the underlying vascular etiologies. To some degree magnetic resonance (MR) imaging seems capable of differentiating these lesions by technical means and by depicting anatomical detail. Microangiopathy, notoriously causing white matter lesions, is focused in a broader sense, including inflammatory and hereditary causes of small vessel disease and corresponding to vascular diseases of the young. Accordingly, interpretation of a given lesion could fail if clinical aspects, such as age, guiding symptoms and acuteness are not taken into account.

References

May 1, 1992·Journal of Neuropathology and Experimental Neurology·V R ChallaM A Bell
Mar 1, 1990·Radiology·L O WahlundL Wetterberg
Jan 1, 1987·Archives of Neurology·V C HachinskiH Merskey
Dec 1, 1996·AJR. American Journal of Roentgenology·J M ProvenzaleT L Ortel
Mar 1, 1997·Stroke; a Journal of Cerebral Circulation·L Pantoni, J H Garcia
Nov 20, 1997·The New England Journal of Medicine·J C Jennette, R J Falk
Mar 2, 1999·Brain : a Journal of Neurology·D KiddT Revesz
Jan 25, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·M RovarisM Filippi
Aug 14, 2001·Journal of Neurology·A Siva
Mar 8, 2002·The New England Journal of Medicine·Jerrold S LevineJoyce Rauch
Mar 20, 2002·Cerebrovascular Diseases·Leonardo Pantoni
Mar 20, 2002·Cerebrovascular Diseases·Martin Dichgans
Jul 10, 2003·Lancet Neurology·Gustavo C RománHelena C Chui
Oct 24, 2003·Neuroradiology·S WeidauerF E Zanella
Nov 5, 2003·Annals of Neurology·R Grant SteenKathleen J Helton
Nov 11, 2003·Brain : a Journal of Neurology·Ahamad HassanHugh S Markus
Dec 25, 2003·Neurology·J O SusacR B Daroff
Jan 30, 2004·JAMA : the Journal of the American Medical Association·Mark C KruitLenore J Launer
Mar 27, 2004·Neuroradiology·K O LövbladD A Rüfenacht
Jun 23, 2004·Lancet Neurology·Elske HoitsmaOm P Sharma
Sep 15, 2004·Archives of Neurology·Richard H Swartz, Ralph Z Kern
Nov 13, 2004·Journal of the Neurological Sciences·Malee S FernandoUNKNOWN MRC Cognitive Function and Ageing Neuropathology Study Group
Jan 11, 2005·Laboratory Investigation; a Journal of Technical Methods and Pathology·Charlotte F J M PeetersRobert M W de Waal
Jan 27, 2005·Molecular Genetics and Metabolism·Tally Lerman-SagieDorit Lev
Mar 12, 2005·Journal of the Neurological Sciences·Kurt A Jellinger
Mar 15, 2005·Alzheimer Disease and Associated Disorders·Helena Chui
Jul 12, 2005·Brain : a Journal of Neurology·Mark C KruitMark A van Buchem
Jul 16, 2005·Journal of Neurology·Peter P Urban, W Müller-Forell
Sep 6, 2005·Stroke; a Journal of Cerebral Circulation·Wiesje M van der FlierPhilip Scheltens
Sep 10, 2005·Neuroradiology·Thomas DuningStefan Knecht
Nov 29, 2005·Magnetic Resonance Imaging·Marie Cécile Henry FeugeasElisabeth Schouman Claeys
Jan 20, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·F Barkhof, P Scheltens
Jan 28, 2006·Stroke; a Journal of Cerebral Circulation·Elisabeth C W van StraatenUNKNOWN LADIS Group

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Citations

Aug 10, 2016·Journal of Geriatric Psychiatry and Neurology·Ayesha KhanClive Ballard
Jul 8, 2017·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Jana KynastMatthias L Schroeter
Feb 13, 2014·Clinical Neuroradiology·S WeidauerE Hattingen
Aug 23, 2020·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Chia-Chen LiuGuojun Bu
Jul 21, 2020·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·Stefan WeidauerElke Hattingen

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