Whitening effect of alpha-bisabolol in Asian women subjects

International Journal of Cosmetic Science
Jongsung LeeDeokhoon Park

Abstract

Although skin pigmentation, which results from the production and distribution of melanin in the epidermis, is the major physiological defence against solar irradiation, hyperpigmentation is a common and distressing problem caused by various inflammatory skin disorders, such as eczema, allergic contact dermatitis and irritant contact dermatitis. We evaluated the effects of a preparation containing alpha-bisabolol on pigmented skin of a group of subjects. The effectiveness of the active compound, alpha-bisabolol, in a base-cream preparation for the treatment of pigmented skin was tested on 28 female subjects as follows: the cream was applied once a day to the back for 8 weeks. These same women also applied a vehicle control cream to the pigmented skin. The results were evaluated by clinical and biophysical test methods. After 8 weeks of treatment of the alpha-bisabolol-containing cream, there was significant lightening effect in the pigmented skin for the majority of the subjects who tested the cream.

References

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Aug 12, 2008·Journal of Dermatological Science·Saebom KimDeokhoon Park

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Citations

Jul 2, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Carlo RomagnoliStefano Manfredini
Dec 21, 2012·The Journal of Investigative Dermatology·Eunmiri RohYoungsoo Kim
Jan 13, 2015·Journal of Cosmetic Dermatology·Changhui ChoJaehyoun Ha
Apr 30, 2015·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·William TuongRaja K Sivamani
Feb 15, 2017·Pharmaceutical Biology·Gisele Façanha Diógenes TeixeiraAdriana Rolim Campos
Oct 14, 2017·International Journal of Toxicology·Monice M Fiume
Aug 31, 2017·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Mayuree Kanlayavattanakul, Nattaya Lourith
May 18, 2021·Pigment Cell & Melanoma Research·Avni Nautiyal, Sarika Wairkar
Sep 17, 2021·The Journal of Dermatological Treatment·Marcus G TanArisa E Ortiz

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