Who achieves low risk drinking during alcohol treatment? An analysis of patients in three alcohol clinical trials

Addiction
Katie WitkiewitzNick Heather

Abstract

There is evidence that low-risk drinking is possible during the course of alcohol treatment and can be maintained following treatment. Our aim was to identify characteristics associated with low-risk drinking during treatment in a large sample of individuals as they received treatment for alcohol dependence. Integrated analysis of data from the Combined Pharmacotherapies and Behavioral Intervention (COMBINE) study, Project MATCH (Matching Alcoholism Treatments to Client Heterogeneity) and the United Kingdom Alcohol Treatment Trial (UKATT) using repeated-measures latent class analysis to identify patterns of drinking and predictors of low-risk drinking patterns during treatment. United States and United Kingdom. Patients (n = 3589) with alcohol dependence receiving treatment in an alcohol clinical trial were primarily male (73.0%), white (82.0%) and non-married (41.7%), with an average age of 42.0 (standard deviation = 10.7). Self-reported weekly alcohol consumption during treatment was assessed using the Form-90 and validated with biological verification or collateral informants. Seven patterns of drinking during treatment were identified: persistent heavy drinking (18.7% of the sample), increasing heavy drinking (9.6%), heavy ...Continue Reading

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Citations

Sep 12, 2018·Alcoholism, Clinical and Experimental Research·Justin KnoxUNKNOWN Alcohol Clinical Trials (ACTIVE) Workgroup
Feb 6, 2019·Scandinavian Journal of Clinical and Laboratory Investigation·Onni NiemeläTiina Laatikainen
Feb 28, 2019·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Mari ArcherOnni Niemelä
Jul 4, 2020·Alcoholism, Clinical and Experimental Research·Justin KnoxUNKNOWN Alcohol Clinical Trials (ACTIVE) Workgroup
Aug 8, 2020·Alcoholism, Clinical and Experimental Research·Katie WitkiewitzJalie A Tucker

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