Who may benefit from preoperative breast MRI? A single-center analysis of 1102 consecutive patients with primary breast cancer

Breast Cancer Research and Treatment
Manuel DebaldHans H Schild

Abstract

Several authors question the potential benefit of preoperative magnetic resonance imaging (MRI) against the background of possible overdiagnosis, false-positive findings, and unnecessary resections in patients with newly diagnosed breast cancer. In order to reveal a better selection of patients who should undergo preoperative MRI after histological confirmed breast cancer, the present analysis was implemented. We aimed to evaluate the influence of preoperative breast MRI in patients with newly diagnosed breast cancer to find subgroups of patients that are most likely to benefit from preoperative MRI by the detection of occult malignant foci. A total of 1102 consecutive patients who underwent treatment for primary breast cancer between 2002 and 2013 were retrospectively analyzed. All patients underwent triple assessment by breast ultrasound, mammography, and bilateral breast MRI. MRI findings not seen on conventional imaging that suggested additional malignant disease was found in 344 cases (31.2 %). Histological confirmed malignant foci were found in 223 patients (20.2 %) within the index breast and in 28 patients (2.5 %) in the contralateral breast. The rate of false-negative biopsies was 31 (2.8 %) and 62 (5.6 %), respectivel...Continue Reading

References

Jan 1, 1997·JAMA : the Journal of the American Medical Association·J G ElmoreA R Feinstein
Mar 21, 2003·AJR. American Journal of Roentgenology·Laura LibermanLee K Tan
Sep 24, 2004·AJR. American Journal of Roentgenology·Francesco SardanelliUNKNOWN Italian Trial for Breast MR in Multifocal/Multicentric Cancer
Nov 19, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christiane K KuhlHans H Schild
Mar 4, 2006·Journal of the American Board of Family Medicine : JABFM·Margaret M EberlMartin C Mahoney
May 2, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Irene L WapnirNorman Wolmark
Oct 2, 2007·Breast Cancer Research and Treatment·Michael BraunChristiane K Kuhl
Feb 9, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Susan Orel
Apr 5, 2008·European Radiology·R M MannC Boetes
May 14, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nehmat HoussamiLes Irwig
May 15, 2008·JAMA : the Journal of the American Medical Association·Christiane K Kuhl
Jul 29, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Monica Morrow, Jay R Harris
Oct 7, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Meagan Elizabeth BrennanStefano Ciatto
Mar 23, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Francesco SardanelliRobin Wilson
Dec 24, 2010·AJR. American Journal of Roentgenology·Robert L GutierrezConstance D Lehman
Apr 5, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J HeilH Junkermann
Oct 18, 2011·Journal of Clinical Epidemiology·Patricia A CarneyJoann G Elmore
Dec 7, 2013·Breast Cancer Research and Treatment·Alice K Fortune-GreeleyWilliam R Carpenter
Jan 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J HeilH Junkermann

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Citations

Mar 2, 2016·The Breast Journal·D David Dershaw
Dec 2, 2015·European Radiology·Jean M SeelyJacqueline Lau
Aug 29, 2016·Translational Oncology·Laura Jeffords MooreDidier Dréau
Dec 28, 2016·AJR. American Journal of Roentgenology·Jiyon LeeVilert A Loving
Sep 30, 2017·Topics in Magnetic Resonance Imaging : TMRI·Beatriz Elena AdradaGaiane Margishvili Rauch
Nov 12, 2017·Hormone Molecular Biology and Clinical Investigation·Christina KaiserWalther Kuhn
Sep 3, 2020·AJR. American Journal of Roentgenology·Dogan S PolatBasak E Dogan
Aug 23, 2019·Radiologia brasileira·Luciana Karla Lira FrançaElvira Ferreira Marques
Apr 15, 2017·Journal of Surgical Oncology·Jennifer TsengKatharine Yao
Dec 7, 2020·Clinical Breast Cancer·Sadaf F JafferbhoySoni Soumian

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