Who should be prioritized for renal transplantation?: Analysis of key stakeholder preferences using discrete choice experiments

BMC Nephrology
Michael D ClarkRobert Higgins

Abstract

Policies for allocating deceased donor kidneys have recently shifted from allocation based on Human Leucocyte Antigen (HLA) tissue matching in the UK and USA. Newer allocation algorithms incorporate waiting time as a primary factor, and in the UK, young adults are also favoured. However, there is little contemporary UK research on the views of stakeholders in the transplant process to inform future allocation policy. This research project aimed to address this issue. Discrete Choice Experiment (DCE) questionnaires were used to establish priorities for kidney transplantation among different stakeholder groups in the UK. Questionnaires were targeted at patients, carers, donors / relatives of deceased donors, and healthcare professionals. Attributes considered included: waiting time; donor-recipient HLA match; whether a recipient had dependents; diseases affecting life expectancy; and diseases affecting quality of life. Responses were obtained from 908 patients (including 98 ethnic minorities); 41 carers; 48 donors / relatives of deceased donors; and 113 healthcare professionals. The patient group demonstrated statistically different preferences for every attribute (i.e. significantly different from zero) so implying that changes ...Continue Reading

References

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Citations

Jul 10, 2014·PharmacoEconomics·Michael D ClarkEsther W de Bekker-Grob
Aug 22, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sabine N van der VeerWim van Biesen
Jan 24, 2014·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Aviva M GoldbergAsha Moudgil
Dec 15, 2015·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Tsung-Tai ChenKuo-Piao Chung
Dec 26, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Heather W O'DellSeth J Karp
Feb 6, 2017·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michael D ClarkRachael L Morton
Jan 8, 2021·BMC Medical Informatics and Decision Making·Darren E StewartRebecca E Goff
Sep 16, 2020·Transplantation Proceedings·Maria Teresa Muñoz SastreEtienne Mullet
Jun 10, 2021·Health Services Research and Managerial Epidemiology·Tariku ShimelsAlison Thompson
Sep 1, 2021·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Zachary PredmoreAlbert W Wu

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