PMID: 9181254May 1, 1997Paper

Whole blood viscosity, blood pressure and cardiovascular risk factors in healthy blood donors

Blood Pressure
E FossumSverre E Kjeldsen

Abstract

Whole blood viscosity contributes to the total peripheral resistance and has been suggested to be a risk factor for cardiovascular disease. Whole blood viscosity was measured using a direct technique in 105 healthy blood donors and in addition to establishing our reference values, the relationship to blood pressure and other cardiovascular risk factors was assessed. Whole blood viscosity correlated with systolic blood pressure (r = 0.29, p = 0.003), cholesterol (r = 0.21, p = 0.034), cholesterol/HDL cholesterol ratio (r = 0.33, p = 0.01), triglycerides (r = 0.37, p < 0.0005), body mass index (r = 0.29, p = 0.003) and waist-hip ratio (r = 0.30, p = 0.002). Subjects with systolic blood pressure > 130 mmHg (n = 16) had higher whole blood viscosity (p = 0.017) than those with lower blood pressure. Whole blood viscosity was significantly lower in women (n = 52) than in men at all shear rates (0.045 > p > 0.001). These results suggest that even in a population of healthy normotensive blood donors of a wide age range and either gender, there are positive correlations between directly assessed whole blood viscosity and a number of the components of the metabolic cardiovascular syndrome including systolic blood pressure, weight and bloo...Continue Reading

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Citations

May 25, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Sahar A Fathallah-ShaykhKenneth R Kensey
Mar 13, 2002·Biosensors & Bioelectronics·Sehyun Shin, Do-Young Keum
Dec 20, 2012·Therapeutic Advances in Chronic Disease·Helga GudmundsdottirIngrid Os
Jan 25, 2012·Vascular Health and Risk Management·Beatriz Y Salazar Vázquez
Nov 17, 2004·Blood Pressure·Ingrid OsAud Høieggen
Feb 10, 2009·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·C IraceA Gnasso
Sep 14, 2004·Journal of Hypertension·Henrik M ReimsSverre E Kjeldsen
Dec 22, 2006·The British Journal of Nutrition·Serena TonstadAud Høieggen
Mar 1, 2012·Hemodialysis International·Shayan ShirazianSteven Fishbane
Oct 20, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·M S BlumbergR F Kirby
Aug 21, 2019·Biomarkers in Medicine·Firdevs Aysenur EkizlerDursun Aras
May 15, 2021·Science & Justice : Journal of the Forensic Science Society·Amanda OrrTheresa Stotesbury

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