Whole-brain 3D FLAIR at 7T using direct signal control.

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Arian BeqiriShaihan J Malik

Abstract

Image quality obtained for brain imaging at 7T can be hampered by inhomogeneities in the static magnetic field, B0 , and the RF electromagnetic field, B1 . In imaging sequences such as fluid-attenuated inversion recovery (FLAIR), which is used to assess neurological disorders, these inhomogeneities cause spatial variations in signal that can reduce clinical efficacy. In this work, we aim to correct for signal inhomogeneities to ensure whole-brain coverage with 3D FLAIR at 7T. The direct signal control (DSC) framework was used to optimize channel weightings applied to the 8 transmit channels used in this work on a pulse-by-pulse basis through the echo train in the FLAIR sequences. 3D FLAIR brain images were acquired on 5 different subjects and compared with imaging using a quadrature-like mode of the transmit array. Precomputed "universal" DSC solutions calculated from a separate set of 5 subjects were also explored. DSC consistently enabled improved imaging across all subjects, with no dropouts in signal seen over the entire brain volume, which contrasted with imaging in quadrature mode. Further, the universal DSC solutions also consistently improved imaging despite not being optimized specifically for the subject being imaged....Continue Reading

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Citations

Jan 18, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Vincent GrasNicolas Boulant
Jun 13, 2019·Topics in Magnetic Resonance Imaging : TMRI·Cem M Deniz
Jun 23, 2020·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Margaret SpiniDaniel M Harrison
Jul 2, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Raphaël Tomi-TricotAlexis Amadon
Nov 24, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Shahrokh Abbasi-RadSteffen Bollmann
Aug 17, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Christoph Stefan AignerSebastian Schmitter

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Software Mentioned

FSL FMRIB Automated Segmentation Tool ( FAST )
EPG
MATLAB
FSL FMRIB Linear Image Registration Tool ( FLIRT )
FSL ( functional MRI of the brain [ FMRIB ] library
CVX
FSL
FAST

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