Whole brain C-arm computed tomography parenchymal blood volume measurements

Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences
Mudassar Kamran, James V Byrne

Abstract

C-arm flat detector computed tomography (FDCT) parenchymal blood volume (PBV) imaging in the neuro-interventional suite is a new technique for which detailed whole brain measurements have not been previously reported. This study aims to create a catalogue of PBV measurements for various anatomical regions encompassing the whole brain, using a three-dimensional volume-of-interest (3D-VOI) analysis. We acquired and analysed 30 C-arm FDCT datasets from 26 patients with aneurysmal subarachnoid haemorrhage (SAH), as part of a prospective study comparing C-arm computed tomography (CT) PBV with magnetic resonance perfusion-weighted imaging (MR-PWI). We calculated the PBV values for various brain regions with an automated analysis, using 58 pre-defined atlas-based 3D-VOIs encompassing the whole brain. VOIs partially or completely overlapping regions of magnetic resonance diffusion weighted imaging (MR-DWI) abnormality or magnetic resonance cerebral blood flow (MR-CBF) asymmetry were excluded from the analysis. Of the 30 C-arm CT PBV datasets, 14 (54%; 12 patients) had areas of restricted diffusion, the majority of which were focal. The PBV values for the cerebral cortex and cerebral white matter were 4.01 ± 0.47 (mean ± SD) and 3.01 ± ...Continue Reading

References

Feb 1, 1990·Brain : a Journal of Neurology·K L LeendersS Herold
Nov 1, 1986·Stroke; a Journal of Cerebral Circulation·T YamaguchiK Suzuki
Oct 23, 2002·Human Brain Mapping·Stephen M Smith
Jun 26, 2007·European Radiology·Willi A Kalender, Yiannis Kyriakou
Mar 21, 2009·AJNR. American Journal of Neuroradiology·A S AhmedD B Niemann
Jan 8, 2010·AJNR. American Journal of Neuroradiology·T BleyD Niemann
Nov 6, 2010·AJNR. American Journal of Neuroradiology·M SharmaR I Aviv
Oct 8, 2011·NeuroImage·Mark JenkinsonStephen M Smith

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Citations

Oct 19, 2019·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Kyle P O'ConnorBradley N Bohnstedt
Mar 18, 2017·Investigative Radiology·Sanjit DattaRebecca Fahrig

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