Whole Exome Sequencing: The Next Phase of Genetics Care

Oncology Nursing Forum
Suzanne M Mahon

Abstract

Exome sequencing is a technique for sequencing all of the genes that code for functioning proteins in the genome. It is now being used to identify mutations in families with suspected hereditary cancer syndromes where single-gene testing or testing for a panel of genes has not been able to detect a mutation. Oncology nurses need to anticipate that more patients and families will be undergoing this testing and be prepared to explain basic concepts about this new technology.

References

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Feb 15, 2014·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Paldeep Singh AtwalLouanne Hudgins
Jun 19, 2014·The New England Journal of Medicine·Leslie G Biesecker, Robert C Green
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Jul 23, 2015·American Journal of Medical Genetics. Part a·Barbara A BernhardtDebra Skinner
Aug 19, 2015·Journal of Genetic Counseling·Shubhangi AroraRachel Mills
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Nov 14, 2015·Current Genetic Medicine Reports·Myra I Roche, Jonathan S Berg
Dec 4, 2015·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Kyle RettererSherri Bale

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Citations

Apr 29, 2020·Genetics and Molecular Biology·Murilo G BorgesIscia Lopes-Cendes

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