Whole-field visual motion drives swimming in larval zebrafish via a stochastic process

The Journal of Experimental Biology
Ruben PortuguesFlorian Engert

Abstract

Caudo-rostral whole-field visual motion elicits forward locomotion in many organisms, including larval zebrafish. Here, we investigate the dependence on the latency to initiate this forward swimming as a function of the speed of the visual motion. We show that latency is highly dependent on speed for slow speeds (<10 mm s(-1)) and then plateaus for higher values. Typical latencies are >1.5 s, which is much longer than neuronal transduction processes. What mechanisms underlie these long latencies? We propose two alternative, biologically inspired models that could account for this latency to initiate swimming: an integrate and fire model, which is history dependent, and a stochastic Poisson model, which has no history dependence. We use these models to predict the behavior of larvae when presented with whole-field motion of varying speed and find that the stochastic process shows better agreement with the experimental data. Finally, we discuss possible neuronal implementations of these models.

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Citations

Dec 4, 2019·Nature Neuroscience·Elena I DragomirRuben Portugues
Dec 4, 2019·Nature Neuroscience·Armin Bahl, Florian Engert
Aug 11, 2020·ELife·Konstantinos LagogiannisMartin P Meyer
Jul 8, 2016·Genetics·Nathalia G HoltzmanJacqueline Morris
Jun 18, 2020·Frontiers in Neural Circuits·Santiago Otero CoronelVioleta Medan
Apr 5, 2017·Annual Review of Neuroscience·Michael B Orger, Gonzalo G de Polavieja

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