Wholegrain Intake and Risk of Type 2 Diabetes: Evidence from Epidemiological and Intervention Studies

Nutrients
Giuseppe Della PepaGabriele Riccardi

Abstract

Type 2 diabetes mellitus (T2DM) is one of the most common metabolic diseases and represents a leading cause of morbidity and mortality because of its related complications. The alarming rise in T2DM prevalence worldwide poses enormous challenges in relation to its social, economic, and a clinical burden requiring appropriate preventive strategies. Currently, lifestyle modifications-including approaches to promote a moderate body weight reduction and to increase regular physical exercise-are the first crucial intervention for T2DM prevention. In the light of the difficulty in reducing body weight and in long-term maintenance of weight loss, quality changes in dietary patterns-in terms of macro and micronutrient composition-can also strongly affect the development of T2DM. This may provide a more practical and suitable preventative approach than simply implementing caloric restriction. Along this line, there is increasing evidence that wholegrain consumption in substitution of refined grains is associated with a reduction of the incidence of several non-communicable chronic diseases. The aim of the present review is to summarize the current evidence from observational and randomized controlled clinical trials on the benefits of w...Continue Reading

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Citations

Nov 5, 2019·Advances in Nutrition·Julie Miller JonesHans J Braun
Jan 23, 2020·International Journal of Food Sciences and Nutrition·Maria TieriGiuseppe Grosso
Oct 23, 2019·International Journal of Food Sciences and Nutrition·Rita PolitoGiovanni Annuzzi
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Mar 1, 2019·Nutrients·Michelle KlerksLuis Manuel Sanchez-Siles
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Feb 10, 2021·The Journal of Nutrition·Simon R SchachtCecilie Kyrø
Feb 17, 2021·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Marilena VitaleRosalba Giacco
Jan 29, 2021·The Journal of Clinical Endocrinology and Metabolism·Feitong WuCostan G Magnussen
Mar 7, 2021·International Journal of Environmental Research and Public Health·Jaana LindströmUrsula Schwab
Jul 2, 2021·Applied Microbiology and Biotechnology·Xuan ZhouLong Liu
Jul 27, 2021·Food Chemistry·Yu PengSrinivas Janaswamy

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