PMID: 18406772Dec 1, 1996Paper

Why are endocrine pituitary cells excitable?

Trends in Endocrinology and Metabolism : TEM
P Mollard, W Schlegel

Abstract

Since 1975, endocrine pituitary cells have been known to be excitable neuronlike cells. Using powerful single-cell approaches, in particular the patch clamp electrophysiological recording technique and the monitoring of Ca(2+) with fluorescent probes, solid evidence has been provided in the last 10 years that intracellular Ca(2+) signals are produced by stimulators and inhibitors of secretion via the modulation of action potentials in isolated pituitary cells. As cytosolic Ca(2+) changes are thought to control numerous cellular functions (for example, secretion, protein synthesis, gene expression, and proliferation) over a long time scale-milliseconds to hours-it is now time to address the long-standing question of what functions would be physiologically controlled by electrical excitability in intact pituitary tissue.

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Citations

Feb 18, 1999·Molecular and Cellular Endocrinology·B H DuvilanskiD Becu-Villalobos
Dec 1, 1996·Trends in Endocrinology and Metabolism : TEM·R Zorec
Dec 1, 1996·Trends in Endocrinology and Metabolism : TEM·S S Stojilkovic, M Tomić
Dec 1, 1996·Trends in Endocrinology and Metabolism : TEM·S S Stojilkovic
May 31, 2011·Journal of Molecular Endocrinology·Marie SchaefferPatrice Mollard
Jul 29, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Zsolt PirgerTibor Kiss
Dec 17, 2011·Cell Calcium·David J HodsonPatrice Mollard
Mar 11, 1999·Journal of Receptor and Signal Transduction Research·G van HaasterenW Schlegel
Nov 10, 2010·Journal of Receptor and Signal Transduction Research·Werner Schlegel
Jun 19, 2015·Cellular and Molecular Life Sciences : CMLS·David J HodsonNathalie C Guérineau
Jan 16, 2002·Current Biology : CB·Nina M StoreyDavid L Armstrong
Jun 28, 2017·Molecular and Cellular Endocrinology·Patrick A FletcherStanko S Stojilkovic
Mar 4, 2000·Endocrinology·X BonnefontP Mollard
Jul 24, 2010·Endocrine Reviews·Stanko S StojilkovicRichard Bertram
Mar 7, 2002·American Journal of Physiology. Cell Physiology·Rosalba I FonterizJavier García-Sancho
Oct 23, 2001·The Journal of Biological Chemistry·C VillalobosJ García-Sancho
Jul 18, 2002·The Journal of Biological Chemistry·Andres MaturanaWerner Schlegel
Nov 13, 2002·The Journal of Biological Chemistry·Pablo ChameroJavier García-Sancho
Jan 21, 2016·American Journal of Physiology. Endocrinology and Metabolism·Alessia TagliaviniMorten Gram Pedersen
Aug 12, 1999·The Journal of Clinical Endocrinology and Metabolism·R RomoliA Spada
Sep 14, 1999·The American Journal of Physiology·A G IglesiasD Becu-Villalobos
Jul 3, 2021·International Journal of Molecular Sciences·Lian Hollander-CohenBerta Levavi-Sivan

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