Why are there regional differences in stem cell transplantation activity? An EBMT analysis

Bone Marrow Transplantation
A GratwohlEuropean Group for Blood and Marrow Transplantation EMBT (JACIE)

Abstract

Differences in the number of hematopoietic SCTs (HSCT), in transplant rates, in indications and in techniques between countries have been reported. They were attributed mainly to differences in the economic situation of the countries or to differences in prevalences of the disease. On the basis of the results of the annual activity survey on HSCT of the European Blood and Marrow Transplantation (EBMT), we have analyzed the factors associated with differences between more than 600 teams participating from more than 40 countries over a time span of 15 years. The results show a more complex situation. The gross national income per capita, number of transplant teams per 10 million inhabitants or per 10,000 km2, team size and team experience all impact on transplant activity. Furthermore, hitherto unknown factors must add to the decisions to perform or not to perform HSCT. These data illustrate that more research is needed to understand the mechanism of HSCT activity and to enable health-care agencies to provide the necessary infrastructure.

References

Apr 26, 2002·British Journal of Haematology·Alois GratwohlUNKNOWN Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT)
Sep 20, 2002·Blood·Alois GratwohlUNKNOWN Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT)
Apr 28, 2006·The New England Journal of Medicine·Edward A Copelan
Dec 7, 2007·Haematologica·Alois GratwohlUNKNOWN European Leukemia Net

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Citations

Sep 20, 2015·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Ian Nivison-SmithJeff Szer
Jan 30, 2010·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Mahmoud AljurfHassan El Solh
Mar 10, 2011·Cancer·Gunnar JuliussonUNKNOWN Swedish Acute Leukemia Registry Group, the Swedish Acute Myeloid Leukemia Group, the Swedish Adult Acute Lymphoblastic Leuke
Jun 1, 2013·Nursing and Midwifery Studies·Zahra FarsiReza Negarandeh
Mar 29, 2011·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Syed O A AhmedMahmoud Aljurf
Nov 3, 2016·Bone Marrow Transplantation·I EspigadoF J Márquez-Malaver
Aug 15, 2009·Current Opinion in Hematology·Alois Gratwohl, Helen Baldomero
Jul 26, 2017·Stem Cells International·Arcangelo LisoEmanuela Turillazzi

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