Why Asplenic Patients Should Not Take Care of the Neighbour's Dog? A Fatal Course of Capnocytophaga canimorsus Sepsis

Case Reports in Infectious Diseases
Patrick LangguthMarcus Both

Abstract

Capnocytophaga canimorsus (CC) belongs to the family Flavobacteriaceae which physiologically occurs in the natural flora of the oral mucosa of dogs and cats. In patients with a compromised immune system, CC can induce a systemic infection with a fulminant course of disease. Infections with CC are rare, and the diagnosis is often complicated and prolonged. We describe a patient with a medical history of prior splenectomy who presented with an acute sepsis and disseminated intravascular coagulation (DIC) and was initially treated on Waterhouse-Friderichsen syndrome (WFS). After the patient had died despite forced treatment in the intermediate care unit, the differential diagnosis of CC was confirmed by culture of blood smears. Later on, a retrospective third-party anamnesis revealed that the patient had contact to his neighbour's dog a few days before disease onset. In conclusion, patients with CC infection can mimic WFS and therefore must be included in the differential diagnosis, especially in patients with a corresponding medical history of dog or cat bites, scratches, licks, or simple exposure.

References

Apr 1, 1976·American Journal of Clinical Pathology·R A Bobo, E J Newton
Mar 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E J Goldstein
Jul 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C PersW Frederiksen
Oct 1, 1996·European Journal of Epidemiology·C LionJ C Burdin
Nov 20, 1998·The Journal of Infection·P BlancheD Sicard
Sep 24, 2005·The New England Journal of Medicine·Patricia V AdemRobert S Daum
Feb 24, 2006·Emerging Infectious Diseases·J Michael JandaWill S Probert
Mar 10, 2009·Veterinary Microbiology·Wim Gaastra, Len J A Lipman
Sep 15, 2011·Journal of Bacteriology·Pablo ManfrediGuy R Cornelis

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Citations

Jan 28, 2021·BMC Ophthalmology·Michael C YangSameh Mosaed

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Methods Mentioned

BETA
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