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Why do human diversity levels vary at a megabase scale?

Genome Research

Sep 1, 2005

Ines HellmannSusan E Ptak

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Abstract

Levels of diversity vary across the human genome. This variation is caused by two forces: differences in mutation rates and the differential impact of natural selection. Pertinent to the question of the relative importance of these two forces is the observation that both diversity withi...read more

Mentioned in this Paper

Mutation Abnormality
Pan troglodytes
Genetic Pedigree
Selection, Genetic
Pan Genus
CpG Clusters
Evolution, Molecular
Recombination, Genetic
Variation (Genetics)
Centromere
Paper Details
References
  • References47
  • Citations95
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Why do human diversity levels vary at a megabase scale?

Genome Research

Sep 1, 2005

Ines HellmannSusan E Ptak

PMID: 16140990

DOI: 10.1101/gr.3461105

Abstract

Levels of diversity vary across the human genome. This variation is caused by two forces: differences in mutation rates and the differential impact of natural selection. Pertinent to the question of the relative importance of these two forces is the observation that both diversity withi...read more

Mentioned in this Paper

Mutation Abnormality
Pan troglodytes
Genetic Pedigree
Selection, Genetic
Pan Genus

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Paper Details
References
  • References47
  • Citations95
12345...

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